BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3263

Peptides:

Sequences

Affinity Values

NCWSSLRGICENLG
SCSWNVERIRGCSV
CWNLKRIGSQGC
CWNLKRIGSQGC
GCVKYRGSVSCQESKT
ACLNHFVSGNMIRC
CPFYDWRCSDF
NVRCYRDVPSCS
EDVVCYGRVDYMPLCV
DCNLWGDDGKYRLCFG
CVKVGLSWIGDCNS
CMEAWQCSLA
QCYPWCRL
CWTYLRGGCSVT
GDCGYHYMCSMT
NMCYLRGKMDCNIV
VCSDHYIGGKEVRC
CCSYGYEKCCNG
SPCRVGYTPC
NCARLYSHQRDYSQVC
CLDRSGGCYTREGYLS
CYPLCRVG
KCDSHYIRGVVACH
GCGYRYMCDMINGL
GDCYPHCRLV
DCLRYRVGSSCS
RCESKGWANTCVSE
CYPLCRVL
RCGLAWCVVLVDQ

[21.7]
[18.8]
[30.7]
[26.4]
[18.0]
[26.1]
[25.0]
[25.9]
[25.2]
[23.6]
[23.9]
[24.6]
[25.1]
[22.1]
[25.0]
[30.9]
[27.4]
[28.6]
[27.7]
[24.4]
[29.0]
[16.2]
[30.2]
[32.8]
[28.9]
[29.6]
[20.7]
[31.1]
[20.8]

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 28825773

Target Name:

Proprotein convertase subtilisin/kexin type 9, PCSK9

Template Name:

Low-density lipoprotein receptor

Structure of Target-Template Complex:

2W2M

2W2N

2W2O

2W2P

2W2Q

3BPS

3GCW

3GCX

3M0C

3P5B

3P5C

Structure of Target-Peptide Complex:

Not determined.

Library Name:

TAFTSWEEYLDWVGSG fusion M13 phage display library (TAFTSWEEYLDWVGSGX(8,10,12,14,16))

Affinity Measurement Method:

ELISA

Affinity Measurement Description:

The s/n ratio is the signal:noise ratio, wherein “signal” and "noise" are the spot phage ELISA signals of phage binding to NeutrAvidin-captured PCSK9 and to NeutrAvidin, respectively. The s/n ratios were shown.

Brief Description:

BiopanningDataSet Comments:

Curator:

Zhongjie Tang

Curation Date:

2017-10-24

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