BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3626

Peptides:

Sequences
TDFLRMMLQEER(8/16)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 35534543

Target Name:

Anti-interferon gamma (IFN-gamma) monoclonal antibody B27

Template Name:

Interferon gamma, IFN-gamma

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

SUT12 M13 phage display library

Affinity Measurement Method:

ELISA

Affinity Measurement Description:

Their binding activity against B27 mAb was detected by phage ELISA. Data were not shown.

Brief Description:

BiopanningDataSet Comments:

The specific peptide sequence recognized by B27 mAb, TDFLRMMLQEER, was retrieved from a phage display random peptide library. Sequence alignment and homology modeling demonstrated that the queried phage peptide sequence and structure were similar to amino acids at position 27–40 (TLFLGILKNWKEES) of the human IFN-γ.

Curator:

Bowen Li

Curation Date:

2023-10-13

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