BDB - Target Details

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Formerly known as MimoDB

An Information Portal to Biopanning Data

As of Monday Dec 23, 2024 there are 3682 sets of biopanning data | BDB Statistics |

BiopanningDataSet
Target
Template
Library
Structure

BDB - Target Details

Target

Target Name: Human beta-FXIIa

Target ID:

1664

Target Type:

Protein>Enzyme

Target Sequence:

Synonyms:

Target Source:

Homo sapiens (Human):9606

Target Structure:

Comments:

FXII is expressed as a zymogen and activated by proteolytic cleavage in a two-step process. A first cleavage gives rise to the α-FXIIa being composed of a heavy and a catalytic light chain held together by a disulfide bond. Further cleavage yields the smaller β-FXIIa, which comprises only the catalytic domain.

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