BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 909

Peptides:

Sequences

SCRGDC(2)
SLPRGD(2)
WMRGDV(1)
GSRGDF(1)
NSRGDF(1)
FLTRGD(1)
AFRGDS(1)
VLFRGD(1)
KSMRGD(1)
GRGDGS(1)
PVRRGD(1)
MRGDRG(1)
SRGDGI(1)
RGDSYP(1)
VLARGD(1)
INSRGD(1)
RGDGYV(1)
RENRGD(1)
GFRGDG(1)
TIRGDQ(1)
TWNHLS(1)

Sequences Features:

Motif:

RGD

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 7535098

Target Name:

Integrin alpha-V-beta-3, integrin αvβ3

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

f3-6mer phage display library (X6)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

Phage were eluted with 0.1 M glycine, pH 2.0, containing 1 mg/mL BSA.

BiopanningDataSet Comments:

Integrin alpha-V beta-3 binds promiscuously to cell-adhesive proteins: vitronectin, fibronectin, and several others containing the RGD motif.

Curator:

Curation Date:

0000-00-00

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