BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 908

Peptides:

Sequences

SCRGDC(2)
DTRGDW(2)
CRGDCA(2)
FMTRGD(1)
CRGDCT(1)
SRGDSF(1)
NCRGDC(1)
SRGDNT(1)
FSRGDR(1)
LNRGDG(1)
WLGRGD(1)
DRGDTY(1)
RGDSFN(1)
NGRIPD(1)
TNGRGP(1)
NGRSRF(1)
TVVRGD(1)
RGDAWL(1)
RGDSLT(1)
TMRGDV(1)
VRGDGV(1)
TRGDPA(1)
RSRNGR(1)
NGRNTV(1)

Sequences Features:

Motif:

RGD

Unique Sequence Number:

Experimental Method:

Phage display (competitive panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 7535098

Target Name:

Integrin alpha-V-beta-3, integrin αvβ3

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

f3-6mer phage display library (X6)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

Phage were eluted with 0.1mL of 1mM GRGDSP peptide in incubation buffer.

BiopanningDataSet Comments:

Integrin alpha-V beta-3 binds promiscuously to cell-adhesive proteins: vitronectin, fibronectin, and several others containing the RGD motif.

Curator:

Curation Date:

0000-00-00

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