BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 898

Peptides:

Sequences
CRGDCL(6) RGDRPG(2) TIRSVD(2) RGDSWG(1) RRGDLR(1) KRGDLP(1) PKRGDL(1) KRGDLG(1) RGDLHL(1) RGDFWQ(1) GRRGDI(1) RGDLWT(1) RGDGWL(1)

Sequences Features:

Motif:

RGD

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

2-3

Reference:

PMID: 7690752

Target Name:

Integrin alpha-5-beta-1, integrin α5β1

Template Name:

Fibronectin, FN

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

f3-6mer phage display library (X6)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

The panning was performed by coating with a low concentration (10ng/well) of integrin. Phage were elute with GRGDSP peptide. CRGDCL was 10-fold more efficient than any of the linear RGD-containing hexapeptides in inhibiting experiment.

BiopanningDataSet Comments:

Curator:

Curation Date:

0000-00-00

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