BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 527

Peptides:

Sequences
PLLQATL(2) RKPGKPV(1) TLHSAQA(1) HNRPRNN(1) RHTHRSH(1) TAPGVST(1) NLTLAWR(1) HTTHMYL(1) WSAPVPN(1) SFRPTPP(1)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 20414975

Target Name:

Heparin-binding growth factor 2, HBGF-2

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-7 phage display library (X7)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

PLLQATL showed high homology to the immunoglobulin-like (Ig-like) domain III (D3) of high-affinity bFGF receptors, FGFR1 (IIIc) and FGFR2 (IIIc). Synthetic PLLQATL peptides mediate strong inhibition of bFGF-induced cell proliferation and neovascularization.

Curator:

Curation Date:

0000-00-00

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