BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 491

Peptides:

Sequences
GPVHKHLPKAHK(3) KPIHHHPHLPLK(2) KPQQHNRPLRHK(2) KIPHPEHPTKFR(2) VFAGKPSHKPPH(2)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 18952877

Target Name:

Magnetic particles (BacMPs)

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-12 phage display library (X12)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

The BacMPs obtained from Magnetospirillum magneticum strain AMB-1 consist of pure magnetite (50 to 100 nm in size) and are covered with a lipid bilayer membrane derived from the invagination of the inner membrane.

BiopanningDataSet Comments:

Forty-eight clones were randomly picked from positive phages and sequenced. The peptides given in the original articles were highly cationic and could bind onto the BacMP membrane. They exhibited antimicrobial activity against Bacillus subtilis but not against Escherichia coli and Saccharomyces cerevisiae.

Curator:

Curation Date:

0000-00-00

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