BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3635

Peptides:

Sequences
SAPHSASDPHYS(9/15) SESAGGNHYSHP(2/15) FYQHSNPWAKYS(1/15) PLSRYKTRAYSC(1/15) VPESRYTVPSAT(1/15)

Sequences Features:

Motif:

PESXXDXXYS

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 33567652

Target Name:

Anti-canine adenovirus 2 (CAdV-2) monoclonal antibody 2C1

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-12 phage display library (X12)

Affinity Measurement Method:

ELISA

Affinity Measurement Description:

The analytical signal was obtained by measuring the absorbance at 450 nm. Data shown were reproduced from Figure 3b.

Brief Description:

CAdV-2-specific neutralizing monoclonal antibodies

BiopanningDataSet Comments:

The high affinity phage clones with mAb 7D7 displayed a consensus motif PESXXDXXYS (X is any aa), similar to the sequence "PESYKDRMYS" observed in the CAdV-2 Hex.

Curator:

Bowen Li

Curation Date:

2023-10-13

First |

Prev |

3635

| Next

| Last