BDB - Target Details

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Target

Target Name: MDDQRDLISNNEQLK peptide

Target ID:

764

Target Type:

Protein>Others

Target Sequence:

P04233 [17-30]

Synonyms:

Target Source:

Homo sapiens (Human):9606

Target Structure:

1A6A, 1ICF, 1IIE, 1L3H, 1MUJ, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 4AEN, 4AH2

Comments:

MDDQRDLISNNEQLK is a synthetic peptide derived from the cytosolic tail of MHC class II associated invariant chain (Ii, HLA class II histocompatibility antigen gamma chain, CD74). This peptide contained a leucine class endosomal sorting signal (LI), known to be recognised as an autonomous functional unit during targeting of class II complexes to antigen processing compartments. The C-terminal lysine was included to allow biotinylation at both ends, as biotin is attached to free amino groups.

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