BDB - Target Details

BiopanningDataSet
Target
Template
Library
Structure

Target

Target Name: Anti-gp120 monoclonal antibody 19b

Target ID:

690

Target Type:

Protein>Monoclonal antibody

Target Sequence:

Synonyms:

Target Source:

Homo sapiens (Human):9606

Target Structure:

Comments:

MAb 19b is a monoclonal human IgG1 obtained from immortalized antibody-producing peripheral cell clones from individuals infected with HIV-1. The ability of MAb 19b to neutralize laboratory-adapted strains of HIV-1, neutralize primary isolates of HIV-1, bind display phage with sequences mimicking the noncontiguous determinant in gpl20 V3 region, and to interfere in the interaction of gpl20 and CCR5 in infectivity of CD4+ cells has been reported.

First |

Prev |

690

| Next

| Last