BDB - Target Details

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Target

Target Name: Extracellular domain of epidermal growth factor tyrosine kinase receptor mutation variant III (EGFRvIII)

Target ID:

2197

Target Type:

Protein>Receptor

Target Sequence:

Synonyms:

Target Source:

Homo sapiens (Human):9606

Target Structure:

Comments:

One of the few known cancer-specific cell surface markers, is the epidermal growth factor (EGF) tyrosine kinase receptor mutation variant III (EGFRvIII). The hEGFRvIII proteins used in this study were purchased from Sino Biological (#29662-H08B). A DNA sequence encoding the human EGFRvIII (NP_001333870.1) (Met1-Lys375) was expressed with a polyhistidine tag at the C-terminus.

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