BDB - Target Details

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Structure

Target

Target Name: Non-structural protein 1, NS1

Target ID:

2142

Target Type:

Protein>Others

Target Sequence:

P29990

Synonyms:

Target Source:

Unknown

Target Structure:

2R29,3EVG,6FLA

Comments:

DENV NS1 is a multifunctional non-structural protein indispensable for virus production, as a new target for inhibition of DENV infection by specific peptides.NS1 is a key viral protein that is required for both DENV replication and dengue disease pathogenesis. The NS1 protein comprises of 352 amino acid residues that share approximately 70% sequence similarity among all four DENV serotypes and 40–50% sequence similarity to other flaviviruses.

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