BDB - Target Details

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Target

Target Name: Tumor necrosis factor ligand superfamily member 13B

Target ID:

Target Type:

Protein>Others

Target Sequence:

Q9Y275

Synonyms:

TNF- and APOL-related leukocyte expressed ligand 1, TALL-1
B lymphocyte stimulator, BLyS
B-cell-activating factor
BAFF
Dendritic cell-derived TNF-like molecule
CD_antigen=CD257

Target Source:

Homo sapiens (Human):9606

Target Structure:

1KXG, 1JH5, 1KD7, 1OQD, 1OQE, 1OSG, 1OTZ, 3V56

Comments:

Tumor necrosis factor ligand superfamily member 13B has two isoforms, i.e. membrane form and soluble form. It abundantly expressed in B cell lineage cells, peripheral blood leukocytes, monocytes and macrophages. This cytokine binds to TNFRSF13B/TACI, TNFRSF17/BCMA and TNFRSF13C/BAFFR, involving in the stimulation of B- and T-cell function and the regulation of humoral immunity.

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