BDB - Target Details

Target

Target Name: Bacteriorhodopsin, BR

Target ID:

1394

Target Type:

Organic molecules or materials

Target Sequence:

P02945

Synonyms:

Bacterioopsin
BO

Target Source:

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium):64091

Target Structure:

1AP9, 1AT9, 1BCT, 1BHA, 1BHB, 1BM1, 1BRD, 1BRR, 1BRX, 1C3W, 1C8R, 1C8S, 1CWQ, 1DZE, 1E0P, 1F4Z, 1F50, 1FBB, 1FBK, 1IW6, 1IW9, 1IXF, 1JV6, 1JV7, 1KG8, 1KG9, 1KGB, 1KME, 1L0M, 1M0K, 1M0L, 1M0M, 1MGY, 1O0A, 1P8H, 1P8I, 1P8U, 1PXR, 1PXS, 1PY6, 1Q5I, 1Q5J, 1QHJ, 1QKO, 1QKP, 1QM8, 1R2N, 1R84, 1S51, 1S52, 1S53, 1S54, 1S8J, 1S8L, 1TN0, 1TN5, 1UCQ, 1VJM, 1X0I, 1X0K, 1X0S, 1XJI, 2AT9, 2BRD, 2I1X, 2I20, 2I21, 2NTU, 2NTW, 2WJK, 2WJL, 2ZFE, 2ZZL, 3COC, 3COD, 3HAN, 3HAO, 3HAP, 3HAQ, 3HAR, 3HAS, 3MBV, 3NS0, 3NSB, 3T45, 3UTV, 3UTW, 3UTX, 3UTY, 3VHZ, 3VI0, 4FPD, 4HWL, 4HYX

Comments:

Just like GPCRs, which form the largest family of drug targets, BR possesses seven transmembrane helices connected by small loops. BR is also well characterized concerning its spectroscopic and biophysical properties. In previous works by Bayburt and his coworkers it was shown that BR can be assembled into nanodiscs in monomeric and oligomeric forms.

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