BDB - Target Details

BiopanningDataSet
Target
Template
Library
Structure

Target

Target Name: Spike glycoprotein

Target ID:

1383

Target Type:

Protein>Others

Target Sequence:

P59594

Synonyms:

S glycoprotein
Peplomer protein
E2

Target Source:

Human SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus):227859

Target Structure:

1WNC, 1WYY, 1ZV7, 1ZV8, 1ZVB, 2AJF, 2BEQ, 2BEZ, 2DD8, 2FXP, 2GHV, 2GHW, 3BGF, 3D0G, 3D0H, 3D0I, 3SCI, 3SCJ, 3SCK, 3SCL

Comments:

Spike glycoprotein cleaves into two proteins: S1 and S2. Spike protein S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. And spike protein S1 is used as the target in the panning.

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