BDB - Target Details

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Target

Target Name: Neural stem cells, NSC

Target ID:

1367

Target Type:

Cell

Target Sequence:

Synonyms:

Target Source:

Mus musculus (Mouse):10090

Target Structure:

Comments:

NSC are undifferentiated multipotent stem cells found in the subventricular and subgranular zones of the mammalian adult brain. NSC represent a good cell type for neuroregenerative purposes not only because of their ability to differentiate into neurons, astrocytes and oligodendrocytes in vitro but also because they do not show tumorigenic potentials upon transplantation in different animal models of neurodegenerative diseases. Moreover, the neural differentiation of NSC can be modulated by specific peptide sequences present in extracellular matrices, in soluble molecules and/or in membrane-bound cell molecules.

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