BDB - Target Details

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Target

Target Name: Matrix metalloproteinase-9, MMP-9

Target ID:

136

Target Type:

Protein>Enzyme

Target Sequence:

P14780

Synonyms:

92 kDa type IV collagenase
92 kDa gelatinase
Gelatinase B, GELB
EC=3.4.24.35

Target Source:

Homo sapiens (Human):9606

Target Structure:

1GKC, 1GKD, 1ITV, 1L6J, 2OVX, 2OVZ, 2OW0, 2OW1, 2OW2, 4H1Q, 4H2E, 4H3X, 4H82, 4HMA

Comments:

Matrix metalloproteinases (MMPs) play critical roles in a multiple number of autoimmunity diseases progression and metastasis of solid tumor. Gelatinases including MMP‐2 and MMP‐9 are extremely overexpressed in multiple pathological processes. MMP‐9 and MMP‐2 breakdown the extracellular matrix component gelatin very efficaciously.

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