BDB - Target Details

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Target Name: Extracellular domain of human ErbB-2, ErbB-2-ECD

Target ID:

1281

Target Type:

Protein>Others

Target Sequence:

Synonyms:

Target Source:

Homo sapiens (Human):9606

Target Structure:

Comments:

The erbB-2 proto-oncogene, also known as HER-2 or neu, is frequently altered in human cancers. This gene encodes an 185 kDa protein, denoted p185, which is also referred to as ErbB-2. ErbB-2 along with three other known homologous proteins, ErbB-1 (epidermal growth factor receptor, EGFR), ErbB-3, and ErbB-4, form the ErbB family or subclass I of receptor tyrosine kinases (RTKs). ErbB-2-ECD is the recombinant extracellular domain of human ErbB-2.

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