BDB - Target Details

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Target

Target Name: Membrane primary amine oxidase

Target ID:

1122

Target Type:

Protein>Enzyme

Target Sequence:

Q16853

Synonyms:

EC=1.4.3.21
Copper amine oxidase
HPAO
Semicarbazide-sensitive amine oxidase, SSAO
Vascular adhesion protein 1, VAP-1

Target Source:

Homo sapiens (Human):9606

Target Structure:

1PU4, 1US1, 2C10, 2C11, 2Y73, 2Y74, 3ALA

Comments:

Vascular adhesion protein-1 (VAP-1/AOC3) is an endothelial cell molecule that is rapidly translocated from the intracellular storage granules to the endothelial cell surface on inflammation. It contributes to several steps in the extravasation cascade and controls trafficking of lymphocytes, granulocytes, and monocytes to sites of inflammation.

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