BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 913

Peptides:

Sequences	Affinity Values
RGDMSLLGEFTSPYG(10) DALSCRGDCVWPTRG(6) RRGDIGPREFSAIVD(4) SPARGDLFRFMGAVH(2) PRDHIARRGDLAFQA(1)	[NT] [100] [NT] [NT] [NT]

Sequences Features:

Motif:

RGD

Unique Sequence Number:

Experimental Method:

Phage display (competitive panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 7535098

Target Name:

Integrin alpha-5-beta-1, integrin α5β1

Template Name:

Fibronectin, FN

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

f3-15mer phage display library (X15)

Affinity Measurement Method:

Binding assay

Affinity Measurement Description:

IC50 (nM) values for the inhibition of binding of adhesive proteins to αvβ3 or α5βl integrins by synthetic peptides were measured using a solid-phase assay.

Brief Description:

Phage were eluted with 0.1mL of 1mM GRGDSP peptide in incubation buffer.

BiopanningDataSet Comments:

Curator:

Curation Date:

0000-00-00

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