BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 793

Peptides:

Sequences
PHCVPRDLSWLDLEANMCLP(18) VTCGSIAEYGWLDLAAACSS(1) PRCMQTSYWMDGLQPESCKG(1) RVCAAPESRLFRGMPLGCDD(1)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 10493820

Target Name:

14-3-3 protein theta

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

X2CX14CX2 phage display library

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

In fact, microtiter wells were coated overnight with GST-14-3-3τ in TBS.', '3', '10493820', 'PHCVPRDLSWLDLEANMCLP efficiently blocked the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.

BiopanningDataSet Comments:

PHCVPRDLSWLDLEANMCLP efficiently blocked the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.

Curator:

Curation Date:

0000-00-00

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