BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 575

Peptides:

Sequences	Affinity Values
CKRDSTWC(8) CKYLWSKC(4) CKYWWSKC(3) CKYWLSRC(3) CKYAWSRC(1) CKYSMSKC(1)	[1.8 ± 0.12] [1.1 ± 0.08] [1.3 ± 0.11] [1.05 ± 0.13] [0.9 ± 0.05] [0.8 ± 0.07]

Sequences Features:

Motif:

K-[RY]-x-W-S-[KR]

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 19520204

Target Name:

Anti-rabies virus polyclonal antibody IgG

Template Name:

Glycoprotein G

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

fdMED1-based CX6C M13 phage display library

Affinity Measurement Method:

ELISA

Affinity Measurement Description:

Absorbance measured at 450nm after substraction of background was shown.

Brief Description:

BiopanningDataSet Comments:

The selected mimotopes were able to inhibit the interactions of the human anti-rabies virus IgG antibodies with rabies virus in a dose-dependent manner. Subcutaneous administration of phage bearing CKRDSTWC induced an rabies virus glycoprotein-specific IgG response in BALB/c mice.

Curator:

Curation Date:

0000-00-00

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