BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 555

Peptides:

Sequences
CPSNVNNIC(1)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (competitive panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 19515773

Target Name:

Glycoprotein Gn, glycoprotein G1

Template Name:

Anti-glycoprotein G1 monoclonal antibody 6B9/F5

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-C7C phage display library (CX7C)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

In fact, density gradient-purified, UV-treated Andes Virus (ANDV) strain CHI-7913 was used in panning. However, glycoprotein G1 is regarded as the target since the peptides were eluted with a monoclonal antibody against the glycoprotein G1. The glycoprotein G1 locates at 4-545 of the glycoprotein precursor (GI:30313865).

BiopanningDataSet Comments:

The phage bearing peptide CPSNVNNIC is the most potent phage identified by elution with the anti-Gn antibody 6B9/F5. It inhibited hantavirus entry by greater than 60%.

Curator:

Curation Date:

0000-00-00

First |

Prev |

555

| Next

| Last