BDB -BiopanningDataSet Details

BiopanningDataSet
Target
Template
Library
Structure

Biopanning Data

BiopanningDataSet ID: 362

Peptides:

Sequences
VWNCERITISRLIN(0.5)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 17959143

Target Name:

Cathepsin S

Template Name:

Protease inhibitors

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

pComb3 X15 phage display library

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

VWNCERITISRLIN showed functional inhibition of cathepsin-S induced sprouting of endothelial cells.Its IC50 is 13 μM. VWNCERITISRLIN showed homology with serine-protease inhibitor 8 from Rattus norvegicus.

Curator:

Curation Date:

0000-00-00

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