BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3220

Peptides:

Sequences
CNWGDRILC(31.3%) CQNNNMTSC(31.3%) CIGNSNTLC(12.5%) CWPANTLKC(12.5%)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (subtractive panning)

Sequencing Platform:

Sequencing Method:

Sanger

Rounds of Panning:

Reference:

PMID: 28428053

Target Name:

Ulcerative colitis (UC) inflamed mucosa

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-7 and Ph.D.-C7C phage display library pool

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

A subtraction step was performed initially by clearing non-specific binders against a freshly harvested normal colon mucosa of healthy volunteers undergoing colonoscopy.

BiopanningDataSet Comments:

We identified one peptide (WPANTLK) able to recognize selectively biopsies of inflamed mucosa of ulcerative colitis (UC) patients.

Curator:

Ning Li

Curation Date:

2017-07-22

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