BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3081

Peptides:

Sequences	Affinity Values
FVRVHTRSSWRVP GVWYTDIRMRDWM	[0.26] [0.032]

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

Target Name:

BTB domain of B cell lymphoma 6(5-129)

Template Name:

BCL-6 corepressors BcoR, SMRT, and N-CoR

Structure of Target-Template Complex:

1R2B(196)

Structure of Target-Peptide Complex:

1R2B(196)

Library Name:

X13 T7 phage display library

Affinity Measurement Method:

ELISA

Affinity Measurement Description:

These peptides exhibited BCL6-selective inhibition in a peptide concentration dependent manner, and the IC50 values (nM) were estimated.

Brief Description:

BiopanningDataSet Comments:

Curator:

Curation Date:

2017-01-13

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