BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 3023

Peptides:

Sequences

SGVYKVAYDWQH(5/34)
SSLELSRSSAAS(2/34)
QTFSRPDWTMYL(2/34)
DPDDTHIMRLLY(1/34)
XKSTASMFTTAR(1/34)
GSAARWPFSVTL(1/34)
LTNTSQLQTRIG(1/34)
SQDIRTWNGTRS(1/34)
IEINATRAGTNL(1/34)
SMRASYPMPTFI(1/34)
GLHTSATNLYLH(1/34)
FPGLFEMVESLN(1/34)
VNMVPLGKNVVQ(1/34)
IDAHFGLRLVND(1/34)
GSGASYQVWRPM(1/34)
MHYGTYTVGYKQ(1/34)
VLKEASHLPYSG(1/34)
GDYGDGFRLLYI(1/34)
VAGLKEQAELDY(1/34)
TSWNMGLTYAGQ(1/34)
VLTNIARGEYMR(1/34)
GQAGGEWILHPL(1/34)
AASSGVTVTLPT(1/34)
GESVSRIDVGSA(1/34)
TTVTGASFSAAY(1/34)
IEASFYDAPRGG(1/34)
KASGSPSGFWPS(1/34)
GSWGLNDSHSYR(1/34)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 27486695

Target Name:

Human blood-brain barrier (BBB) cellular model

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-12 phage display library (X12)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

From the panning experiment of a 12-mer library, the SGVYKVAYDWQH (SGV) peptide sequence was selected and internalisation studies suggested that SGV internalises through a clathrin-mediated mechanism and that it increases the uptake of a cargo in endothelial cells.

Curator:

Curation Date:

2016-10-18

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