BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 2905

Peptides:

Sequences

NCEDYLPGWFCT(14/29)
DCNARQAYSRCA(1/29)
GCDWYAIWRTCI(1/29)
HCLSRRAVLFCA(1/29)
GCPPVVWRPSCS(1/29)
TCLPDLQHSTCY(1/29)
GCPRTTHDQACA(1/29)
FCATPHTRPLCH(1/29)
RCVPSREDPWCL(1/29)
QCYKTEARITCY(1/29)
SCERQYTPSECQ(1/29)
KCRRGFLAHSCQ(1/29)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 25944054

Target Name:

Plasmodium berghei female gametes

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

LX-8 phage display library (XCX8CX)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

After three rounds of selection, close to half of the recovered phages displayed the same NCEDYLPGWFCT peptide, named FG1 for Female Gamete peptide 1, which binds specifically to Plasmodium berghei female gametes. FG1 inhibits gamete fertilization and interferes with further development of the parasite in the mosquito.

Curator:

Curation Date:

0000-00-00

First |

Prev |

2905

| Next

| Last