BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 2889

Peptides:

Sequences
SLQPTEHNKFWL(2) MTTPTESHKFGH(1) DLLRPSEKNKFF(1) SYTPSELRVFQT(1) TPAPSERMHFDS(1) SPSELQKFQTRS(1) KSTPSEIRHFDY(1)

Sequences Features:

Motif:

[TS]-P-[ST]-E-x(2)-[KH]-F

Unique Sequence Number:

Experimental Method:

Phage display (subtractive panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 25520269

Target Name:

Anti-coagulation factor VIII polyclonal antibody IgG from haemophilia A patient 5

Template Name:

Coagulation factor VIII

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-12 phage display library (X12)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

For positive selections, IgGs from FVIII inhibitor-positive plasma was immobilized on streptavidin-coated beads via a biotin-conjugated goat anti-human IgG. For negative selections, IgGs from a plasma pool of healthy individuals negative for FVIII-specific antibodies were immobilised likewise.

BiopanningDataSet Comments:

Curator:

Curation Date:

0000-00-00

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