BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 2885

Peptides:

Sequences
NYTHPGS(1) WTHPGNR(1) NFTHPGS(1) WTHPGAQ(1) SFTHPGQ(1) YTHPGAA(1)

Sequences Features:

Motif:

T-H-P-G

Unique Sequence Number:

Experimental Method:

Phage display (subtractive panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 25520269

Target Name:

Anti-coagulation factor VIII polyclonal antibody IgG from haemophilia A patient 1

Template Name:

Coagulation factor VIII

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-C7C phage display library (CX7C)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

For positive selections, IgGs from FVIII inhibitor-positive plasma was immobilized on streptavidin-coated beads via a biotin-conjugated goat anti-human IgG. For negative selections, IgGs from a plasma pool of healthy individuals negative for FVIII-specific antibodies were immobilised likewise.

BiopanningDataSet Comments:

Curator:

Curation Date:

0000-00-00

First |

Prev |

2885

| Next

| Last