BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 1530

Peptides:

Sequences
TPITQLL(10) QTSSAAL(4) STFTTTL(4) SLPLPKP(2)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 21533529

Target Name:

The first and second extracellular loops of CCR5

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

Ph.D.-7 phage display library (X7)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

These peptides could significantly protect against and reduce the severity of EAE. The infiltration of monocytes and lymphocytes into the spinal cord decreased significantly in treated mice, while abundant infiammatory cells and demyelination were observed in spinal cords of EAE mice.

Curator:

Curation Date:

0000-00-00

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