BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 1374

Peptides:

Sequences
CHASIYDFGSC(18) CVYALIMPPLC(1)

Sequences Features:

Motif:

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 10760806

Target Name:

Anti-CCR5 monoclonal antibody 3A9

Template Name:

C-C chemokine receptor type 5

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

pVIII-9aa.Cys phage display library (CX9C)

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

All clones were tested by capture ELISA for reactivity with mAb 3A9 and 23 of 26 clones showed strong reactivity. After sequencing, 19 nonameric peptide inserts could be identified. For phage CHASIYDFGSC, the motif SIYD aligned to residues at the N terminus and FG to residues on the first extracellular loop.

Curator:

Curation Date:

0000-00-00

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