BDB -BiopanningDataSet Details

Biopanning Data

BiopanningDataSet ID: 1120

Peptides:

Sequences
CWKLLGSEEEC(15) CPCFLLGCC(15) CWHKDLLGC(4) CWSMELLGC(1) CPPDLFWYC(4) CPEDLYFFC(3) CPEDFIFFC(1)

Sequences Features:

Motif:

L(2)-G

Unique Sequence Number:

Experimental Method:

Phage display (common panning)

Sequencing Platform:

Sequencing Method:

Sanger sequencing

Rounds of Panning:

Reference:

PMID: 11381078

Target Name:

Integrin alpha-M-beta-2, integrin αMβ2

Template Name:

Not determined.

Structure of Target-Template Complex:

Not determined.

Structure of Target-Peptide Complex:

Not determined.

Library Name:

CX7C and CX9C phage display library pool

Affinity Measurement Method:

Affinity Measurement Description:

Brief Description:

BiopanningDataSet Comments:

LLG sequences exposed on ICAM-1 and on von Willebrand factor at sites of vascular injury play a role in the binding of leukocytes, and CPCFLLGCC and peptidomimetics derived from it could provide a therapeutic approach to inflammatory reactions.

Curator:

Curation Date:

0000-00-00

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