Primary dataset analytics

CROSSTCR Statistics

Interactive statistics for the TCR Cross-Reactive pMHCs Dataset only. The views summarize group complexity, biological composition, evidence coverage, sequence features, and release sources from the current v1.4.0 primary release.

Analysis scope

Primary table only

All statistics on this page are computed from TCR_CrossReactive_pMHCs.v1.4.0.json. The supplementary pMHC-centered view is intentionally excluded so the analysis reflects the main CROSSTCR resource.

Cross-reactive groups Inspect how many records, peptides, MHC alleles, and references support each group.

Evidence coverage Separate experimental evidence, binding outcomes, assay types, and structure-linked records.

Interactive filters Filter by MHC class, peptide origin, evidence level, structure availability, and release year.

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Current data coverage

Primary release snapshot

Counts update with the active filters. The unfiltered view reflects the complete TCR Cross-Reactive pMHCs Dataset.

- records

- cross-reactive groups

- paired TCRs

- peptides

- MHC alleles

- references

- structure-linked records

Group complexity

Cross-reactive group structure

Click a Top group bar to open that group in the Dataset page.

Group-size distribution

Records per cross-reactive group, shown for group sizes 2-9 only.

Top cross-reactive groups

Largest groups under the current filters; bars link to grouped records.

Biological composition

MHC and antigen context

Composition charts support category-level filtering. Click MHC class or peptide origin categories to refine the full dashboard.

MHC class

Normalized MHCI/MHCII composition.

Peptide origin

Curated antigen origin labels, including not-reported entries.

Peptide species

Top source species or pathogen groups represented in the main table.

Clinical context

Clinical-context annotations and reporting completeness.

Evidence and assay coverage

Experimental support and reporting completeness

Evidence and missingness charts identify which records have experimental support, assay annotations, and structure-linked context.

Assay type

Top assay types after filtering.

Structure availability

Structure-linked records versus records without reported PDB structure.

Missingness overview

Percentage of not-reported values in key interpretation fields.

Filtered evidence summary

Compact record-level balance across evidence, structures, and references.

Sequence and pMHC features

Length, similarity, and paired-chain features

Distribution views summarize CDR3 lengths, peptide length, peptide similarity, and paired alpha/beta CDR3 length combinations used for cross-reactivity interpretation.

CDR3 length distribution

Alpha and beta chain CDR3 lengths shown together.

CDR3 length pairing

Joint distribution of paired CDR3 alpha and beta lengths.

Peptide similarity

Binned peptide similarity values from the main table.

Peptide length

Peptide length distribution in amino acids.

TCR alpha chain V and J gene usage distribution

TCR alpha V/J gene usage

Distribution of TRA V and J gene combinations in the primary TCR-centered dataset.

TCR beta chain V and J gene usage distribution

TCR beta V/J gene usage

Distribution of TRB V and J gene combinations in the primary TCR-centered dataset.

Release and source landscape

Time and source coverage

Release-year and reference summaries show how the primary dataset is distributed across publication/source evidence.

Records by release year

Current filtered record count by release year.

Top references

Most frequent source references or domains represented in the selected subset.