The HMMCAS has been developed and maintained by HLAB. Like all other tools, bugs will have occurred during the development phase. If you find any bug in the program, please let us know. Any other problems or questions, do not hesitate to contact the corresponding author: Prof. Jian Huang (hj@uestc.edu.cn). We appreciate your feedback very much. It will certainly help us make HMMCAS better for the scientific community of basic and applied research.