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    General information
    AgoID:Ago0098
    Accession:NP_036286.2
    ProteinName:protein argonaute-2 isoform 1
    AlternativeNames:
    Organism:Homo sapiens
    AgoType:eAgo
    Experimentally-verified:No
    ProteinSequence:NP_036286.2.fasta
    SequenceLength:859
    GeneName:AGO2, PPD, Q10, CASC7, EIF2C2, LESKRES, LINC00980
    GeneID:27161
    LocusTag:
    CodingRegion:NC_000008.11 (140520156..140642406, complement)
    GO enrichment:GO terms: positive regulation of trophoblast cell migration GO:1901165
               negative regulation of amyloid precursor protein biosynthetic process GO:0042985
               production of siRNA involved in RNA interference GO:0030422
               siRNA binding GO:0035197
               positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
               mRNA cap binding complex GO:0005845
               RNA 7-methylguanosine cap binding GO:0000340
               negative regulation of translational initiation GO:0045947
               positive regulation of nuclear-transcribed mRNA catabolic process deadenylation-dependent decay GO:1900153
               gene silencing by RNA GO:0031047
               translation initiation factor activity GO:0003743
               post-embryonic development GO:0009791
               translational initiation GO:0006413
               positive regulation of angiogenesis GO:0045766
               translation GO:0006412
               protein C-terminus binding GO:0008022
               cell junction GO:0030054
               dendrite GO:0030425
               core promoter sequence-specific DNA binding GO:0001046
               RNA polymerase II complex binding GO:0000993
               polysome GO:0005844
               regulation of gene silencing by miRNA GO:0060964
               ribonucleoprotein complex GO:1990904
               positive regulation of transcription by RNA polymerase II GO:0045944
               endoribonuclease activity GO:0004521
               RNA phosphodiester bond hydrolysis endonucleolytic GO:0090502
               RNA binding GO:0003723
               nucleoplasm GO:0005654
               miRNA metabolic process GO:0010586
               nucleus GO:0005634
               mRNA cleavage involved in gene silencing by miRNA GO:0035279
               miRNA loading onto RISC involved in gene silencing by miRNA GO:0035280
               RNA secondary structure unwinding GO:0010501
               RISC-loading complex GO:0070578
               post-transcriptional gene silencing by RNA GO:0035194
               miRNA mediated inhibition of translation GO:0035278
               production of miRNAs involved in gene silencing by miRNA GO:0035196
               RISC complex GO:0016442
               pre-miRNA processing GO:0031054
               miRNA binding GO:0035198
               Wnt signaling pathway calcium modulating pathway GO:0007223
               single-stranded RNA binding GO:0003727
               double-stranded RNA binding GO:0003725
               P-body GO:0000932
               negative regulation of gene expression GO:0010629
               positive regulation of gene expression GO:0010628
               cytoplasm GO:0005737
               cytosol GO:0005829
               protein binding GO:0005515
               metal ion binding GO:0046872
               membrane GO:0016020

    Domain information
    DomainAnnotation:
    DomainSequence:Download
    DmReference:
    DomainSource:AGONOTES
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