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General information
AgoID:	Ago0001
Accession:	Q8CJG0.3
ProteinName:	Protein argonaute-2
AlternativeNames:	(Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
Organism:	Mus musculus (Mouse)
AgoType:	eAgo
Experimentally-verified:	Yes
ProteinSequence:	Q8CJG0.3.fasta
SequenceLength:	860
GeneName:	Ago2,Eif2c2, Kiaa4215
GeneID:	239528
LocusTag:
CodingRegion:	NC_000081.7 (72973474..73056796, complement)
GO enrichment:	GO terms: mRNA cleavage involved in gene silencing by miRNA GO:0035279
	positive regulation of trophoblast cell migration GO:1901165
	negative regulation of amyloid precursor protein biosynthetic process GO:0042985
	mRNA cap binding complex GO:0005845
	siRNA binding GO:0035197
	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
	negative regulation of translational initiation GO:0045947
	RNA 7-methylguanosine cap binding GO:0000340
	positive regulation of nuclear-transcribed mRNA catabolic process deadenylation-dependent decay GO:1900153
	extracellular exosome GO:0070062
	post-embryonic development GO:0009791
	positive regulation of angiogenesis GO:0045766
	mRNA binding GO:0003729
	protein C-terminus binding GO:0008022
	miRNA loading onto RISC involved in gene silencing by miRNA GO:0035280
	RNA secondary structure unwinding GO:0010501
	RISC-loading complex GO:0070578
	pre-miRNA processing GO:0031054
	production of miRNAs involved in gene silencing by miRNA GO:0035196
	miRNA mediated inhibition of translation GO:0035278
	miRNA binding GO:0035198
	single-stranded RNA binding GO:0003727
	gene silencing by RNA GO:0031047
	double-stranded RNA binding GO:0003725
	RISC complex GO:0016442
	regulation of translation GO:0006417
	RNA binding GO:0003723
	nucleic acid binding GO:0003676
	cytoplasm GO:0005737
	endoribonuclease activity GO:0004521
	endonuclease activity GO:0004519
	nuclease activity GO:0004518
	hydrolase activity GO:0016787
	nucleoplasm GO:0005654
	metal ion binding GO:0046872
	core promoter sequence-specific DNA binding GO:0001046
	RNA polymerase II complex binding GO:0000993
	polysome GO:0005844
	ribonucleoprotein complex GO:1990904
	positive regulation of transcription by RNA polymerase II GO:0045944
	cytosol GO:0005829
	positive regulation of gene expression GO:0010628
	miRNA metabolic process GO:0010586
	P-body GO:0000932
	nucleus GO:0005634

Domain information
DomainAnnotation:
DomainSequence:	Download
DmReference:
DomainSource:	AGONOTES