Details

Antibody

Heavy Chain: K
Mutation: NULL

>3ZTJ_K|Chain G, I, K|FI6V3 ANTIBODY HEAVY CHAIN|HOMO SAPIENS (9606) QVQLVESGGGVVQPGRSLRLSCAASGFTFSTYAMHWVRQAPGKGLEWVAVISYDANYKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDSQLRSLLYFEWLSQGYFDYWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK

Light Chain: L
Mutation: NULL

>3ZTJ_L|Chain H, J, L|FI6V3 ANTIBODY LIGHT CHAIN|HOMO SAPIENS (9606) DIVMTQSPDSLAVSLGERATINCKSSQSVTFNYKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQHYRTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Antigen

Chain: F
Mutation: NULL

>3ZTJ_F|Chain B, D, F|HEMAGGLUTININ HA2 CHAIN|INFLUENZA A VIRUS (387139) GLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKG

Interaction

1、Solvent accessible surface areas (SASA) were calculated (Naccess V2.1.1) for each residue in antibody and antigen, respectively. The residues with SASA loss in binding of more than 1Ų were classified as interacting residues.

Interacting residues (ΔSASA based)

K: TYR52 GLN97 LEU98 ARG99 L: PHE27 ASN28 TYR32 TYR92 ARG93 F: ILE18 ASP19 GLY20 TRP21 LEU38 LYS39 THR41 GLN42 ALA43 ILE45 ASP46 GLN47 ILE48 ASN49 LEU52 ASN53 ILE56 GLU57

Interacting residues (Atom distance based)

Within the threshold, the structure has no interacting amino acids and cannot be displayed. This may be due to the following reasons:
1. The method used to determine the structure is electron microscopy or nuclear magnetic resonance, which results in too low resolution;
2. the coordinates of some amino acids involved in the interaction in the structure were not detected due to technical limitations. The results are less based on atomic coordinates, but the antibody does target the antigen.