Details
Structure visualisation
Entry information
| Complex | |
| AACDB_ID: | 224 |
| PDBID: | 2BSE |
| Chains: | F_C |
| Organism: | Lactococcus virus P2, Lama glama |
| Method: | XRD |
| Resolution (Å): | 2.70 |
| Reference: | 10.1038/nsmb1029 |
| Antibody | |
| Antibody: | 2BSE VHH |
| Antibody mutation: | No |
| INN (Clinical Trial): | |
| Antigen | |
| Antigen: | receptor-binding protein |
| Antigen mutation: | No |
| Durg Target: | |
Sequence information
Antibody
Chain: F
Mutation: NULL
| >2BSE_F|Chain D, E, F|LLAMA IMMUNOGLOBULIN|LAMA GLAMA (9844) QVQLQESGGGLVQAGGSLRLSCTASRRTGSNWCMGWFRQLAGKEPELVVALNFDYDMTYYADSVKGRFTVSRDSGKNTVYLQMNSLKPEDTAIYYCAARSGGFSSNRELYDGWGQGTQVTVSS |
Antigen
Chain: C
Mutation: NULL
| >2BSE_C|Chain A, B, C|RECEPTOR BINDING PROTEIN|LACTOCOCCUS VIRUS P2 (254252) MTIKNFTFFSPNSTEFPVGSNNDGKLYMMLTGMDYRTIRRKDWSSPLNTALNVQYTNTSIIAGGRYFELLNETVALKGDSVNYIHANIDLTQTANPVSLSAETANNSNGVDINNGSGVLKVCFDIVTTSGTGVTSTKPIVQTSTLDSISVNDMTVSGSIDVPVQTLTVEAGNGLQLQLTKKNNDLVIVRFFGSVSNIQKGWNMSGTWVDRPFRPAAVQSLVGHFAGRDTSFHIDINPNGSITWWGANIDKTPIATRGNGSYFIK |
Interaction
1、Solvent accessible surface areas (SASA) were calculated (Naccess V2.1.1) for each residue in antibody and antigen, respectively. The residues with SASA loss in binding of more than 1Å2 were classified as interacting residues.
Interacting residues (ΔSASA based)
| F: THR28 GLY29 SER30 ASN31 LEU47 ASN52 ASP54 TYR55 MET57 THR58 TYR59 ARG99 SER100 GLY101 GLY102 PHE103 SER104 SER105 GLU108 LEU109 ASP111 C: GLN198 LYS199 GLY200 TRP201 ASN202 TRP207 VAL217 SER219 HIS232 ASP234 ASN236 PRO237 ASN238 SER240 THR242 TRP244 |
2、We defined interacting paratope-epitope residues by a distance cutoff of < 5Å . Two amino acids are considered as interacting residues if they have at least one atom within a distance of 5 Å from any atom.
Interacting residues (Atom distance based)
