Details
Structure visualisation
Entry information
| Complex | |
| AACDB_ID: | 101 |
| PDBID: | 1MVF |
| Chains: | B_D |
| Organism: | Camelus dromedarius, Escherichia coli |
| Method: | XRD |
| Resolution (Å): | 1.65 |
| Reference: | 10.1074/jbc.M302336200 |
| Antibody | |
| Antibody: | cAbmaz1 VHH |
| Antibody mutation: | No |
| INN (Clinical Trial): | |
| Antigen | |
| Antigen: | MazE protein |
| Antigen mutation: | No |
| Durg Target: | |
Sequence information
Antibody
Chain: B
Mutation: NULL
| >1MVF_B|Chain A, B|immunoglobulin heavy chain variable region|Camelus dromedarius (9838) QVQLVESGGGSVQAGGSLRLSCAASGFTYSRKYMGWFRQAPGKEREGVAAIFIDNGNTIYADSVQGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAASSRWMDYSALTAKAYNSWGQGTQVTVSSRGRHHHHHH |
Antigen
Chain: D
Mutation: NULL
| >1MVF_D|Chain C[auth D], D[auth E]|PemI-like protein 1|Escherichia coli (562) MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW |
Interaction
1、Solvent accessible surface areas (SASA) were calculated (Naccess V2.1.1) for each residue in antibody and antigen, respectively. The residues with SASA loss in binding of more than 1Å2 were classified as interacting residues.
Interacting residues (ΔSASA based)
| B: TYR33 PHE52 ASN55 ASN57 THR58 ILE59 TRP102 MET103 ASP104 TYR105 SER106 ALA107 LEU108 D: ILE17 PRO18 ALA19 THR20 LEU21 GLN23 ALA24 LEU25 ASN26 |
2、We defined interacting paratope-epitope residues by a distance cutoff of < 5Å . Two amino acids are considered as interacting residues if they have at least one atom within a distance of 5 Å from any atom.
Interacting residues (Atom distance based)
