Details
Structure visualisation
Entry information
| Complex | |
| AACDB_ID: | 10 |
| PDBID: | 1BQL |
| Chains: | HL_Y |
| Organism: | Mus musculus, Colinus virginianus |
| Method: | XRD |
| Resolution (Å): | 2.60 |
| Reference: | 10.1002/(SICI)1097-0134(199609)26:1<55::AID-PROT5>3.0.CO;2-F |
| Antibody | |
| Antibody: | HYHEL-5 Fab |
| Antibody mutation: | No |
| INN (Clinical Trial): | |
| Antigen | |
| Antigen: | BOBWHITE QUAIL Lysozyme |
| Antigen mutation: | No |
| Durg Target: | |
Sequence information
Antibody
Heavy Chain: H
Mutation: NULL
| >1BQL_H|Chain B[auth H]|HYHEL-5 FAB (HEAVY CHAIN)|Mus musculus (10090) EVQLQQSGAELMKPGASVKISCKASGYTFSDYWIEWVKQRPGHGLEWIGEILPGSGSTNYHERFKGKATFTADTSSSTAYMQLNSLTSEDSGVYYCLHGNYDFDGWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVP |
Light Chain: L
Mutation: NULL
| >1BQL_L|Chain A[auth L]|HYHEL-5 FAB (LIGHT CHAIN)|Mus musculus (10090) DIVLTQSPAIMSASPGEKVTMTCSASSSVNYMYWYQQKSGTSPKRWIYDTSKLASGVPVRFSGSGSGTSYSLTISSMETEDAATYYCQQWGRNPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC |
Antigen
Chain: Y
Mutation: NULL
| >1BQL_Y|Chain C[auth Y]|BOBWHITE QUAIL LYSOZYME|Colinus virginianus (9014) KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNSQATNRNTDGSTDYGVLQINSRWWCNDGKTPGSRNLCNIPCSALLSSDITATVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL |
Interaction
1、Solvent accessible surface areas (SASA) were calculated (Naccess V2.1.1) for each residue in antibody and antigen, respectively. The residues with SASA loss in binding of more than 1Å2 were classified as interacting residues.
Interacting residues (ΔSASA based)
| L: ASP1 ILE2 SER28 VAL29 ASN30 TYR31 TYR33 ASP49 TRP90 GLY91 ARG92 PRO94 H: SER30 ASP31 TRP33 TRP47 GLU50 LEU52 SER55 GLY56 SER57 THR58 ASN59 GLY99 ASN100 TYR101 ASP102 Y: GLN41 THR43 ASN44 ARG45 ASN46 THR47 ASP48 GLY49 THR51 TYR53 ARG61 ASP66 GLY67 LYS68 THR69 PRO70 GLY71 SER72 SER81 LEU84 |
2、We defined interacting paratope-epitope residues by a distance cutoff of < 5Å . Two amino acids are considered as interacting residues if they have at least one atom within a distance of 5 Å from any atom.
Interacting residues (Atom distance based)
