2026 CGRRAGGSC CTRRAGGGC CSRAGGLGC CSYAGGLGC CDVAGGLGC CGAGGLGAC CGAGGWGVC CAGGTFKPC CLGEVAGGC CGSNDAGGC CYRGIAGGC CAGGVAGGC CGGLAGGFC CLLAGGVLC CLVVSAGGC CRTQAGGVC CAGGFGEQC CAGGLIDVC CAGGSTWTC CAGGDWWWC CAGGGLLMC CVAAGGGLC CLYGAGGSC CCALAGGCC CIGAGGVHC A-G-G 25 Phage display (in vivo) PMID:11821895 Human prostate Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2027 CGRRGSAGC(2) CRPGRRGSC(1) CSGRRGPRC(1) CGLGRRNGC(1) CGGRRSQTC(1) CLWDGRRHC(1) CGRRSVLTC(1) CFGRRNLFC(1) CGAGRRYWC(1) CGRRLWATC(1) CGVGRRFGC(1) CLEMVGRRC(1) CLSSIGRRC(1) CGRRWIDVC(1) CGRREEGLC(1) CGRRVLGRC(1) CRGLMGRRC(1) CRFLLGRRC(1) CPGVGRRLC(1) CGVIDGRRC(1) CADGRRLGC(1) CAGRRAQIC(1) CYGRRAREC(1) CPGRRLRMC(1) CGGRRVTLC(1) CEQGGRRLC(1) CSGRRLHPC(1) CFDHSGRRC(1) CGRRDVAIC(1) G-R-R 29 Phage display (in vivo) PMID:11821895 Human skin Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2028 CGGHPRLAC CGGHWRVNC CGGHILEVC CGGHRAQSC CGDGGHRPC CSCVGGHSC CGSGVGGHC CVRGWGGHC CWRGWGGHC G-G-H 9 Phage display (in vivo) PMID:11821895 Human skin Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2029 CWGSKGTVC CTGSLGTVC CWGTVSDAC CATGTVGPC CVVGTVAWC CWVVGTVTC CRVVHGTVC CGTVRFFSC G-T-V 8 Phage display (in vivo) PMID:11821895 Human skin Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2030 CPKHGVLWC CSGVLWYHC CGVLWAFGC CQARGVLWC CGVLVSRMC CGTVGVLVC CVGVLLPAC CGGVLLLSC CSGVLIHDC CPYFGVLAC CFFVSGVLC CLLAGGVLC CGEMGGVLC CGRAYGVLC CSGVLDG CWWGGVLGC CVWSRGVLC CGVLRGVSC CSFGVLRGC CKGSVGVLC CGGHFGVLC CWMDVGVLC CAFRVGVLC CGVGVLRKC G-V-L 35 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2031 CMEGRGAGC CSEGRGFMC CVEGRNSKC CVEGRYTPC CFNEGRQMC CFEGRSRSC CDHVVEGRC CWDGTEGRC CLDWREGRC CRGCEGRVC CMTPEGRVC CRLFEGRVC CREGRRMCC CTQFEGRRC CSMEGRMFC CPGSAEGRC CGEGRILAC CEGRFSAWC CEGRSDIWC CEGRARWLC CEGRERWRC E-G-R 21 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2032 CCQCGFGVC(1) CRGGFGVRC(1) CAVGFGVIC(2) CIVGFGVAC(1) CGNFGVVWC(1) CDEPFGVAC(1) CVWFGVGSC(1) CWFGVSLSC(1) CFGVGQWAC(1) CSMRFGVSC(1) CRFGVWTGC(1) CRFGVGRVC(1) CSGLFGVYC(1) CMKGVFGVC(1) CAFGVVSDC(1) CLYAFGVVC(1) CKVFGVVEC(1) CFGVRTDLC(1) CTIFGVRRC(1) F-G-V 19 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2033 CVWPRFGGC(1) CSRFGGRVC(1) CMKFGGRLC(1) CRFGGALRC(1) CERFGGDEC(1) CFGGSVAPC(1) CWFGGSVQC(1) CFGGSWSLC(1) CLLFGGSAC(1) CMRLFGGTC(1) CFGGFFMYC(2) CEFGGQMNC(1) CTFGGLILC(1) CGNSFGGWC(1) CRTFGGAGC(1) CWVFGGKSC(1) CRGFGGLSC(1) CLWPSFGGC(1) F-G-G 18 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2034 CGERISGPC CGERLSSRC CTEGERAGC CWWLGERVC CWAWAGERC CGVISGERC CGPGGERGC CLGGGERDC CDIAGERVC CSRSKGERC CKRKGERVC CSRPGERQC CCMRRGERC CTLRGERNC CFGERNRIC CRGERWDLC CGERTALLC G-E-R 17 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2035 CPSGTSSWC CSMSGTGMC CLFDVSGTC CVTGLSGTC CNMVISGTC CGVSGTLGC CRSGTPGKC CGRSGTSGC CIYSGTLWC CCSGTLFCC CRSGTLQTC CLGSGTWSC CESGTATGC CFTERSGTC CRYLRSGTC CPLGSSGTC S-G-T 16 Phage display (in vivo) PMID:11821895 Human multiple organs Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) A patient received an intravenous infusion of the unselected random phage library, and 15 min after infusion tissue biopsies were obtained to provide histopathological diagnosis and to recover phage from various organs. 2036 CTARSPWIC(12) 1 Phage display (common panning) 3 PMID:22797828 Nd2O3 nanocrystals Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) This phage displayed sequence TARSPWI flanked by two cysteines exhibited about 24,000 times greater affinity towards Nd2O3 nanocrystals than a random phage in the same-tube competitive binding assay. 2037 AYQRFDDVASRF(10) VNLRMDDHDWSR(6) KWNMNEDQIFFR(3) AYKQTYHETTWF(3) INLQTSTLMSHT(1) IHLDHGTVAPIW(1) [ED]-D 6 Phage display (competitive panning) 5 PMID:22868630 Human mammary carcinoma cell line SK-BR-3 Not determined. Not determined. Not determined. Ph.D.-12 phage display library (X12) After the first selection, the acid eluted buffer was changed with Herceptin?. The shown sequences of peptides revealed that 40% peptides shared a consensus sequence (AYQRFDDVASRF).Consensus amino acid motifs (DD/ED) appeared at high frequencies. 2038 AEHYTFPKHSVWDIPYI AEQTPKHSLWTPYTYPA AEAHYKHSCRQDFCPTL K-H-S 3 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library 2039 AEKNIVTYIPRGDMPTM AEYKHPRGDSPTHHQFG AEARIMRGDMPSSNHFT 3 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library 2040 AEPGLAISCKRDVCITS 1 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library 2041 AETQYPHPVCRGDCNMW AEPRGDWSTFRTHDTLF R-G-D 2 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library Peptides contained KGD sequences suggesting that these fusion peptides bound to the glycoprotein IIb-IIIa(GPIIb-llla). 2042 AETLLDQGGHAVQLGDV 1 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library 2043 AEFSKKTSEAFPVWRLM AEASVRSYLHKRLEHPL AEFYRPSLLTAWYSNMP AESASFSCRSDYCITST AELFSTHYLAFKEDYSQ AEEKHWLYVPDWTTAP AEEKHWLYSPCLVHCP 7 Phage display (common panning) 4 DOI:10.1002/ddr.430330203 Human Platele Not determined. Not determined. Not determined. X15 M13 phage display library 2044 YRHSVI LRHSVI WRHSVV LRHSVV R-H-S-V 4 Phage display (common panning) 3 PMID:1376364 Anti-P53 monoclonal antibody PAb240 p53 protein Not determined. Not determined. f3-6mer phage display library (X6) ELISA A wild-type phage control gave a background signal of 0.080. Phage clones giving a signal above 0.230 (~65%) were considered positive (data not shown). The average signal obtained from the positive clones was 0.452; the maximal signal 0.757. All four sharing a common RHSV tetrapeptide core sequence.The C-terminal residue of the encoded hexapeptide as either valinr or isoleucine. 2045 ADGGAQGTA(21) PGPSRAHFL(19) LSSREPQAR(11) RLTRELYAQ(9) YTQKHKHQA(4) 5 Phage display (subtractive panning) 3 PMID:7504991 Sera from RA patients Not determined. Not determined. Not determined. pVIII-9aa phage display library (X9) ELISA,Competition experiment The binding of the sera from RA patients and normal individual (both not included in the pool) to the phage displaying pepl (ADGGAQGTA) was investigated by ELISA. The percentage of the sera positive for pepl was significantly raised in RA (44%) compared to the controls (13%). Similar results were obtained with the other selected phages. Then the reactivity of the phage displaying pepl was investigated in detail. In competitive ELISA, the binding of the sera to phage-coated plates was significantly inhibited by the phage itself, whereas no inhibition was obtained with an unrelevant phage displaying a different peptide. In competitive inhibition a synthetic peptide corresponding to the peptide displayed by the phage (ADGGAQGTA), inhibited the binding of the sera to the phage by 56%. Phages isolated during the second round of panning on RA sera were incubated with 100 pg of ammonium-precipitated immunoglobulins obtained from a pool of 40 normal individuals. After panning for 10 min on a plate coated with streptavidin, the non adherent phages (depletion step) were collected. RA sera was used in the positive selection. Ammonium-precipitated immunoglobulins from a pool of 40 normal individuals were used in the negtive selection. 2046 APWLYGPA 1 Phage display (common panning) 3 PMID:7685300 Anti-LeY antigen monoclonal antibody B3 Not determined. Not determined. Not determined. X8 and CX8C phage display library pool Phage that bind to the biotinylated mAb B3 were enriched by several cycles of biopanning on streptavidin-coated petri dishes. Alanine-scanning mutagenesis of the sequence coding for this peptide indicates that four residues,PWLY,were critical for binding to the mAb. 2047 HGRFILPWWYAFSPS RFRGLISLSQVYLSP ARVSFWRYSSFAPTY W-Y-A-[WF]-S-P 3 Phage display (common panning) 3 PMID:9237904 Thomsen-Friedenreich antigen (T antigen, TF antigen) Not determined. Not determined. Not determined. f3-15mer phage display library (X15) Wells of the microtiter plates were first coated with streptavidin, washed with TPBS (phosphate buffered saline, pH 7.4, 0.5% (v/v) Tween-20), and blocked with 3% (w/v) BSA prior to addition of biotinylated antigens. Phages were incubated with antigen prior to washing and elution. In the last two rounds of some procedures, phages were pre-incubated with the biotinylated antigens before the streptavidin capture. A putative consensus sequence of W-Y-A-[WF]-S-P was present in the most frequently occurring clone, P30(HGRFILPWWYAFSPS). 2048 GSWYAWSPLVPSAQI W-Y-A-[WF]-S-P 1 Phage display (common panning) 3 PMID:9237904 Thomsen-Friedenreich antigen (T antigen, TF antigen) Not determined. Not determined. Not determined. f88-15mer phage display library (X15) Wells of the microtiter plates were first coated with streptavidin, washed with TPBS (phosphate buffered saline, pH 7.4, 0.5% (v/v) Tween-20), and blocked with 3% (w/v) BSA prior to addition of biotinylated antigens. Phages were incubated with antigen prior to washing and elution. In the last two rounds of some procedures, phages were pre-incubated with the biotinylated antigens before the streptavidin capture. A putative consensus sequence of W-Y-A-[WF]-S-P was present in the most frequently occurring clone, P10(GSWYAWSPLVPSAQI). 2049 CGFECVRQCPERC 1 Phage display (in vivo) 3 PMID:9664085 Mouse lung Not determined. Not determined. Not determined. CX3CX3CX3C phage display library Mice were first anesthetized with Avertin and then injected intravenously (tail vein) with phage peptide library.Organs were then weighed, homogenized, and the phage were rescued by infection with K91kan bacteria. 2050 CGFELETC CTLRDRNC CIGEVEVC 3 Phage display (in vivo) 3 PMID:9664085 Mouse lung Not determined. Not determined. Not determined. fdMED1-based CX6C M13 phage display library Mice were first anesthetized with Avertin and then injected intravenously (tail vein) with phage peptide library.Organs were then weighed, homogenized, and the phage were rescued by infection with K91kan bacteria.