176 1VWN B-P [B-P]>B: LS(25,27)+YSAV(43,45-47)+SY(52,54)+W79+RASTW(84,86,88,90,92)+WL(108,110)+D128 [B-P]>P: CHPQFC(1-6) The site residues were obtained through computing contacts by a distance ≤ 4Å. 177 2E9W A-C:2, B-D:3 [A-C]>A: D72+R122+Y125+R181+IKR(201,203,205)+S240+NSWH(260-263)+G265 [B-D]>B: D72+T74+R122+Y125+R181+IKR(201,203,205)+S240+NSWH(260-263)+G265 [A-C]>C: R7+TNN(9-11)+SD(53,54)+T57+L60+DKVN(77,78,80,81)+DD(84,85)+E88+F102 [B-D]>D: R7+TNN(9-11)+SD(53,54)+T57+L60+DKVN(77,78,80,81)+DDVE(84,85,87,88)+K99 178 1DF8 A-BTN201A, B-BTN202B [A-BTN201(A)]>A: NLS(23,25,27)+Y43+VN(47,49)+W79+S88+T90+WL(108,110)+D128 [B-BTN202(B)]>B: NLS(23,25,27)+Y43+VN(47,49)+W79+S88+T90+W108+D128 179 1LUQ A-BTN5100(A), A-BTN5200(B), B-BTN5200(B) [A-BTN5100(A)]>A: NLS(1023,1025,1027)+Y1043+VGN(1047-1049)+ST(1088,1090)+WL(1108,1110)+D1128 [A-BTN5200(B)]>A: W120 [B-BTN5200(B)]>B: NLS(2023,2025,2027)+Y2043+VGN(2047-2049)+W2079+AST(2086,2088,2090)+W2108+D2128 180 1MEP A-BTN5100(A), D-BTN5100(A), B-BTN5200(B), C-BTN5200(B), B-BTN5300(C), C-BTN5300(C), D-BTN5400(D) [A-BTN5100(A)]>A: N23+S27+Y43+VN(47,49)+W79+ST(88,90)+WL(108,110) [D-BTN5100(A)]>D: W120 [B-BTN5200(B)]>B: NLS(23,25,27)+Y43+VGN(47-49)+W79+SW(88,90)+W108 [C-BTN5200(B)]>C: W120 [B-BTN5300(C)]>B: W120 [C-BTN5300(C)]>C: N23+S27+Y43+VGN(47-49)+W79+SW(88,90)+W108+L110 [D-BTN5400(D)]>D: N23+S27+Y43+VGN(47-49)+W79+ASW(86,88,90)+W108 181 1MK5 A-BTN5100(A), B-BTN5100(A), A-BTN5200(B), B-BTN5200(B) [A-BTN5100(A)]>A: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN5100(A)]>B: W120 [A-BTN5200(B)]>A: W120 [B-BTN5200(B)]>B: NLS(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+WL(108,110)+D128 182 1N43 A-BTN5100(A), B-BTN5200(B), C-BTN5300(C), D-BTN5400(D) [A-BTN5100(A)]>A: S27+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN5200(B)]>B: LS(25,27)+YS(43,45)+GN(48,49)+W79+ST(88,90)+W108+D128 [C-BTN5300(C)]>C: S27+YSVGN(43,45,47-49)+W79+STW(88,90,92)+W108+D128 [D-BTN5400(D)]>D: LS(25,27)+YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 183 1N9M A-BTN5100(A), B-BTN5200(B), C-BTN5300(C), D-BTN5400(D) [A-BTN5100(A)]>A: NLA(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 [B-BTN5200(B)]>B: NLA(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 [C-BTN5300(C)]>C: NLA(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 [D-BTN5400(D)]>D: NLA(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 184 1NDJ A-BTN5100(A), D-BIN5100(A), B-BTN5200(B), C-BTN5200(B), B-BTN5300(C), C-BTN5300(C), D-BTN5400(D) [A-BTN5100(A)]>A: N23+S27+FSVN(43,45,47,49)+W79+AST(86,88,90)+W108+D128 [D-BIN5100(A)]>D:W120 [B-BTN5200(B)]>B: NLS(23,25,27)+FSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [C-BTN5200(B)]>C: W120 [B-BTN5300(C)]>B: W120 [C-BTN5300(C)]>C: NLS(23,25,27)+FSVN(43,45,47,49)+W79+STW(88,90,92)+WL(108,110)+D128 [D-BTN5400(D)]>D: NLS(23,25,27)+FSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 185 1NQM A-BTN150(A), B-BTN150(A), A-BTN350(B), B-BTN350(B), C-BTN550(C), D-BTN550(C), C-BTN750(D), D-BTN750(D) [A-BTN150(A)]>A: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN150(A)]>B: K320 [A-BTN350(B)]>A: K120 [B-BTN350(B)]>B: N223+S227+YSVN(243,245,247,249)+W279+ST(288,290)+W308+D328 [C-BTN550(C)]>C: N423+S427+YSVN(443,445,447,449)+W479+ST(488,490)+W508+D528 [D-BTN550(C)]>D: K720 [C-BTN750(D)]>C: K520 [D-BTN750(D)]>D: N623+S627+WSVN(643,645,647,649)+W679+ST(688,690)+W708+D728 186 1STP A-BTN300(A) [A-BTN300(A)]>A: N23+S27+YSVN(43,45,47,49)+W79+AST(86,88,90)+WW(108,120)+D128 187 1SWD A-BTN300(A), D-BTN300(A), A-BTN600(D), D-BTN600(D) [A-BTN300(A)]>A: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+ASTW(86,88,90,92)+W108+D128 [D-BTN300(A)]>D: W120 [A-BTN600(D)]>A: A120 [D-BTN600(D)]>D: NLS(23,25,27)+Y43+VGN(47-49)+W79+ASTW(86,88,90,92)+WL(108,110)+D128 188 1SWE A-BTN300(A), B-BTN400(B), B-BTN500(C), C-BTN500(C), A-BTN600(D), D-BTN600(D) [A-BTN300(A)]>A: N23+S27+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN400(B)]>B: N23+S27+YSVN(43,45,47,49)+W79+AST(86,88,90)+W108+D128 [B-BTN500(C)]>B: W120 [C-BTN500(C)]>C: NLS(23,25,27)+YS(43,45)+GN(48,49)+W79+STW(88,90,92)+W108+D128 [A-BTN600(D)]>A: W120 [D-BTN600(D)]>D: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 189 1SWG A-BTN600(A), D-BTN600(A), B-BTN700(B), C-BTN700(B), C-BTN800(C), A-BTN900(D), D-BTN900(D) [A-BTN600(A)]>A: NLS(23,25,27)+YS(43,45)+W79+ASTW(86,88,90,92)+W108+D128 [D-BTN600(A)]>D: W120 [B-BTN700(B)]>B: NLS(23,25,27)+YS(43,45)+W79+AST(86,88,90)+WL(108,110)+D128 [C-BTN700(B)]>C: W120+AS(138,139) [C-BTN800(C)]>C: NLS(23,25,27)+YS(43,45)+W79+ASTW(86,88,90,92)+WL(108,110)+D128 [A-BTN900(D)]>A: W120 [D-BTN900(D)]>D: NLS(23,25,27)+YS(43,45)+W79+STW(88,90,92)+W108+D128 190 1SWK A-BTN5100(A), B-BTN5200(B), C-BTN5200(B), A-BTN5400(D), D-BTN5400(D) [A-BTN5100(A)]>A: N23+S27+YSVGN(43,45,47-49)+W79+ASTW(86,88,90,92)+W108+D128 [B-BTN5200(B)]>B: N23+S27+YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 [C-BTN5200(B)]>C: W120 [A-BTN5400(D)]>A: W120 [D-BTN5400(D)]>D: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 191 1SWN A-BTN300(A), C-BTN500(C), D-BTN600(D) [A-BTN300(A)]>A: N23+S27+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 [C-BTN500(C)]>C: N23+S27+YSVN(43,45,47,49)+W79+S88+D128 [D-BTN600(D)]>D: N23+S27+YSVN(43,45,47,49)+W79+ST(88,90)+D128 192 1SWP A-BTN300(A), B-BTN400(B), D-BTN600(D) [A-BTN300(A)]>A: NLS(23,25,27)+YSVN(43,45,47,49)+W79+AST(86,88,90)+W108+D128 [B-BTN400(B)]>B: N23+S27+YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 [D-BTN600(D)]>D: NLS(23,25,27)+YSVN(43,45,47,49)+W79+AST(86,88,90)+W108+D128 193 1SWR A-BTN300(A), D-BTN300(A), B-BTN400(B), C-BTN400(B), B-BTN500(C), C-BTN500(C) [A-BTN300(A)]>A: NLS(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+WL(108,110)+D128 [D-BTN300(A)]>D: K121 [B-BTN400(B)]>B: N23+S27+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [C-BTN400(B)]>C: K121 [B-BTN500(C)]>B: K121 [C-BTN500(C)]>C: NLS(23,25,27)+YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 194 1SWT A-BTN500(A), B-BTN600(B) [A-BTN500(A)]>A: N23+S27+YSVN(43,45,47,49)+W79+ST(88,90) [B-BTN600(B)]>B: N23+S27+YS(43,45)+N49+ST(88,90) 195 2F01 A-BTN5100(A), B-BTN5200(B) [A-BTN5100(A)]>A: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN5200(B)]>B: NLS(23,25,27)+YSVN(43,45,47,49)+W79+AST(86,88,90)+W108+D128 196 2GH7 A-BTN5100(A), B-BTN5200(B) [A-BTN5100(A)]>A: NLS(23,25,27)++YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [B-BTN5200(B)]>B: NLS(23,25,27)++YSVN(43,45,47,49)+W79+ST(88,90)+W108+D128 197 2IZF B-BTN300(B), D-BTN301(D) [B-BTN300(B)]>B: NLS(23,25,27)++YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 [D-BTN301(D)]>D: NLS(23,25,27)++YSVGN(43,45,47-49)+W79+AST(86,88,90)+W108+D128 198 2IZG B-BTN300(B), D-BTN301(D) [B-BTN300(B)]>B: NLS(23,25,27)++YSVGN(43,45,47-49)+W79+ST(88,90)+WL(108,110)+D128 [D-BTN301(D)]>D: NLS(23,25,27)++YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 199 2IZH B-BTN300(B), B-BTN300(D), D-BTN300(D) [B-BTN300(B)]>B: N23+S27+YSVGN(43,45,47-49)+W79+ST(88,90)+WL(108,110)+D128 [B-BTN300(D)]>B: W120 [D-BTN300(D)]>D: N23+S27+YSVGN(43,45,47-49)+W79+ST(88,90)+W108+D128 200 2IZI A-BTN300(A) [A-BTN300(A)]>A: NLS(23,25,27)+YSVGN(43,45,47-49)+W79+STW(88,90,92)+WL(108,110)+D128