1251 KIX domain of p300/CBP Protein>Others Unknown 1252 HNSCC cell line MDA167Tu Cell Homo sapiens (Human):9606 1253 Dysplastic skin Organ and tissue Mus musculus (Mouse):10090 1254 The human cell lines 16HBE14o- Cell Homo sapiens (Human):9606 1255 LOX-1 Protein>Receptor Q9EQ09 Oxidized low-density lipoprotein receptor 1 Ox-LDL receptor 1 Lectin-like oxidized LDL receptor 1 Lectin-like oxLDL receptor 1 Lectin-type oxidized LDL receptor 1 Mus musculus (Mouse):10090 LOX-1 is a receptor normally expressed at low levels exclusively on venous and arterial vascular endothelial cells but strongly upregulated in dysfunctional endothelium associated with hypertension and atherogenesis. 1256 PMCA398 Protein>Others Unknown PM Ca2+ pumps are encoded by four plasma membrane Ca2+-ATPase (PMCA) genes, and their transcripts can be alternatively spliced.The isoform PMCA1b is most widely expressed. The PM Ca2+ pump protein models show ten transmembrane and five extracellular domains. The second putative extracellular domain of PMCA1b in rabbit contains the residues 401-413 (KRPWLAECTPIYI. Including additional amino acids flanking this sequence, replacing serine for cysteine, and adding a cysteine at the COOH terminus, the peptide PMCA398 (WVQKRPWLAESTPIYIQYFVKC) was synthesized. 1257 U87-MG glioma cells Cell Homo sapiens (Human):9606 1258 Human melanoma cell line MeWo Cell Homo sapiens (Human):9606 1259 Bacterial cell wall precursor lipid I Organic molecules or materials Unknown Phage display screens made use of lipid I inspired targets in both natural and enantiomeric forms.First,by doing so the amount of chemical space explored in the screen is effectively doubled.Secondly,it was considered that L-peptides selected in the screen that possess high affinity for natural lipidI/II might in fact be toxic towards the E.coli used in the amplification step of the phage display experiment ,so using enantiomeric forms was viewed as a way of avoiding any such negative selection bias. 1260 Anti-CK 8/18 complex monoclonal antibody Protein>Monoclonal antibody Mus musculus (Mouse):10090 K94 monoclonal antibody, a tumor-associated autoantibody purified from another B-cell hybridoma clone derived from a mouse model of HCC, was analyzed and identified as an anti-cytokeratin (CK) 8/18 complex antibody. 1261 Eukaryotic initiation factor (eIF)4E Protein>Others Homo sapiens (Human):9606 eIF4E initiates cap-dependent translation by binding to the cap structure found at the 59 end of mRNA. eIF4E is part of the large eIF4F complex which includes other proteins such as eIF4G and eIF4A. eIF4F forms a complex with the 40S ribosomal subunit and eIF3, which then shuttles along the 59-untranslated region (59-UTR) of the mRNA until it arrives at the AUG initiation codon. 1262 Karilysin catalytic domain, Kly18 Protein>Enzyme D0EM77 Karilysin protease Bacteroides forsythus (Tannerella forsythensis):28112 2XS3, 2XS4, 4IN9 Karilysin, a newly identified metalloprotease isolated from T. forsythia is secreted as a 472-residue protein and has the following composition; a 20-residue signal sequence, a 14-residue pro-peptide, an 18 kDa catalytic peptidase domain and a 30 kDa C-terminal domain of unknown function. 1263 Calretinin, CR Protein>Others P22676 29 kDa calbindin Homo sapiens (Human):9606 Calretinin (CR), a Ca+2-binding protein highly expressed in subpopulations of neurons in thebrain, inhibits CDI and enhances CDF by binding directly to α12.1. 1264 Human IgA, hIgA Protein>Polyclonal antibody Homo sapiens (Human):9606 IgA is secreted in the mucus as a dimer (secretory form of IgA) connected by a joining chain via intermolecular disulfide bridges, whereas the major form of IgA in plasma is monomeric. IgA has two subclasses: IgA1 and IgA2. 1265 Unphosphorylated ERα LBD Protein>Others Unknown The Estrogen Receptor (ER) belongs to the Nuclear Receptor (NR) superfamily of ligand-inducible transcription factors that bind to DNA response elements and cofactor proteins to control gene transcription. There are two ER isoforms, ERα and ERβ, which both bind estradiol as a natural ligand and share the multidomain features of NRs, which includes a C-terminal Ligand Binding Domain (LBD) with significant homology (60%). 1266 Phosphorylated ERβ LBD, ERβ LBD-P Protein>Others Unknown The Estrogen Receptor (ER) belongs to the Nuclear Receptor (NR) superfamily of ligand-inducible transcription factors that bind to DNA response elements and cofactor proteins to control gene transcription. There are two ER isoforms, ERα and ERβ, which both bind estradiol as a natural ligand and share the multidomain features of NRs, which includes a C-terminal Ligand Binding Domain (LBD) with significant homology (60%). ERβ LBD-P contained a phosphorylated Y488. 1267 Phosphorylated ERα LBD, ERα LBD-P Protein>Others Unknown The Estrogen Receptor (ER) belongs to the Nuclear Receptor (NR) superfamily of ligand-inducible transcription factors that bind to DNA response elements and cofactor proteins to control gene transcription. There are two ER isoforms, ERα and ERβ, which both bind estradiol as a natural ligand and share the multidomain features of NRs, which includes a C-terminal Ligand Binding Domain (LBD) with significant homology (60%). ERa LBD-P contained a phosphorylated Y537. 1268 Unphosphorylated ERβ LBD Protein>Others Unknown The Estrogen Receptor (ER) belongs to the Nuclear Receptor (NR) superfamily of ligand-inducible transcription factors that bind to DNA response elements and cofactor proteins to control gene transcription. There are two ER isoforms, ERα and ERβ, which both bind estradiol as a natural ligand and share the multidomain features of NRs, which includes a C-terminal Ligand Binding Domain (LBD) with significant homology (60%). 1269 Anti-PI-LPS monoclonal antibody 1E4 Protein>Monoclonal antibody Mus musculus (Mouse):10090 1270 Bone marrow-derived dendritic cells, BMDCs Cell Mus musculus (Mouse):10090 1271 Mouse liver Organ and tissue Mus musculus (Mouse):10090 1272 Mouse spleen Organ and tissue Mus musculus (Mouse):10090 1273 Mouse visceral adipose tissues Organ and tissue Mus musculus (Mouse):10090 1274 DOX-SAM Organic molecules or materials Unknown Doxorubicin, a commonly used cancer chemotherapy agent, elicits several potent biological effects, including synergistic-antitumor activity in combination with cisplatin. A derivative of doxorubicin underinvestigation is synthesized to form a self-assembled monolayer (SAM). 1275 Monoclonal antibody 6D10 Protein>Monoclonal antibody Mus musculus (Mouse):10090