1076 Gold Inorganic molecules or materials None 1077 Titanium, Ti Inorganic molecules or materials None 1078 Stainless steel Inorganic molecules or materials None 1079 Bulk steel (edges) Inorganic molecules or materials None 1080 Iridium oxide, IrO2 Inorganic molecules or materials None 1081 Anti-RESA monoclonal antibody MAb 18/2 Protein>Monoclonal antibody Mus musculus (Mouse):10090 1082 Grass carp hemorrhage virus Virus Grass carp hemorrhagic virus:128986 Grass carp hemorrhage virus (GCHV), a member of Reoviridae, causes severe hemorrhagic disease of grass carp (Ctenopharyngodon idellus) in China 1083 Newcastle disease virus, NDV Virus Newcastle disease virus (isolate AF2240) (NDV):351071 Newcastle disease virus (NDV) which causes a major disease in poultry, is grouped under the family of Paramyxoviridae. 1084 Apical membrane antigen 1, AMA1 Protein>Others Q7KQK5 Plasmodium falciparum (isolate 3D7):36329 1Z40, 2Q8A, 2Q8B, 2Z8V, 2Z8W, 3SRJ, 3ZWZ 1085 Regulatory protein E2 Protein>Others P03120 Human papillomavirus type 16:333760 1BY9, 1DTO, 1R8P, 1ZZF, 2NNU, 2Q79, 3MI7 Plays an accessory role in initiation of DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex. 1086 Human antibodies eluted from the surface of infected red blood cell (iRBC) Protein>Polyclonal antibody Homo sapiens (Human):9606 1087 Large envelope protein Protein>Others P03139 L glycoprotein L-HBsAg, LHB Large S protein Large surface protein Major surface antigen Hepatitis B virus genotype D subtype adw (isolate United Kingdom/adyw/1979) (HBV-D):10419 The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane. 1088 Interferon alpha/beta receptor 2, IFN-R-2 Protein>Receptor P48551 IFN-alpha binding protein, IFN-alpha/beta receptor 2 Interferon alpha binding protein Type I interferon receptor 2 Homo sapiens (Human):9606 1N6U, 1N6V, 2HYM, 2KZ1, 2LAG, 3S8W, 3S9D, 3SE3, 3SE4 Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. 1089 Envelope glycoprotein E2 Protein>Others Q99IB8 [384-750] NS1 gp68 gp70 Hepatitis C virus genotype 2a (isolate JFH-1) (HCV):356411 2KZQ, 2LIF, 2XXD, 2XYM, 3I5K, 4AEP, 4AEX, 4E76, 4E78, 4E7A 1090 Interleukin-10, IL-10 Protein>Others P22301 Cytokine synthesis inhibitory factor, CSIF Homo sapiens (Human):9606 1ILK, 1INR, 1J7V, 1LK3, 1Y6K, 2H24, 2ILK Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. 1091 Ganglioside GM1 Organic molecules or materials Homo sapiens (Human):9606 GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both Cholera toxin and E. coli heat-labile enterotoxin. 1092 Hemagglutinin, HA Protein>Others Influenza A virus (strain A/Puerto Rico/8/1934 H1N1):211044 1RU7, 1RVX, 1RVZ Hemagglutinin (HA) in the membrane of type A influenza viruses recognizes sialylglycoconjugate receptors on the host cell surface at an initial step in the infection process; consequently, HA inhibitors are considered potential candidates for antiviral drugs. 1093 Hemagglutinin, HA Protein>Others O40714 Influenza A virus (A/Wuhan/359/1995(H3N2)):63106 Hemagglutinin (HA) in the membrane of type A influenza viruses recognizes sialylglycoconjugate receptors on the host cell surface at an initial step in the infection process; consequently, HA inhibitors are considered potential candidates for antiviral drugs. 1094 α form of poly(L-lactide) crystalline films Inorganic molecules or materials ??? None PLLA is one of the most commonly used synthetic polymers in the biomedical field because of its many excellent physical properties such as thermal stability, mechanical properties, biocompatibility, and biodegradability to nontoxic products. 1095 Anti-biotin polyclonal antibody Protein>Polyclonal antibody Capra hircus (Goat):9925 The anti-biotin antibody was obtained from Sigma(B3640), which was produced in goat with Biotin-KLH conjugate as immunogen. 1096 GSI-B4 isolectin Protein>Others Q8W1R6 Griffonia simplicifolia:3850 1GNZ, 1HQL 1097 Anti-pig Xenoreactive Natural Antibodies, XNAs Protein>Polyclonal antibody Homo sapiens (Human):9606 Human anti-pig XNAs, primarily of IgM isotype, were eluted from porcine aortic endothelial cell. They were captured to be the target of biopanning by biotinylated mouse anti-human IgM, which was imobilized by streptavidin coated on the surface of the culture plates. 1098 Fc domain of IgG (IGHG1,IGHG2,IGHG3,IGHG4) Protein>Others P01857, P01859, P01860, P01861 Ig gamma chain C region, Human IgG Fc fragment Homo sapiens (Human):9606 IGHG1: 1AJ7, 1AQK, 1BEY, 1D5B, 1D5I, 1D6V, 1DFB, 1DN2, 1E4K, 1FC1, 1FC2, 1FCC, 1GAF, 1H3T, 1H3U, 1H3V, 1H3W, 1H3X, 1H3Y, 1HKL, 1HZH, 1I7Z, 1L6X, 1N7M, 1OP3, 1OQO, 1OQX, 1T83, 1T89, 1VGE, 2DTS, 2GJ7, 2I5Y, 2IWG, 2J6E, 2JB5, 2JB6, 2O5X, 2O5Y, 2O5Z, 2OSL, 2QAD, 2QL1, 2QQK, 2QQL, 2QQN, 2QR0, 2R56, 2RCJ, 2RCS, 2VXQ, 2WAH, 3AGV, 3AVE, 3AY4, 3B2U, 3B2V, 3BDY, 3BE1, 3BKY, 3BN9, 3BQU, 3C08, 3C09, 3C2S, 3CFJ, 3CFK, 3CSY, 3D0L, 3D0V, 3D6G, 3D85, 3DJ9, 3DNK, 3DO3, 3DRO, 3DRQ, 3DVG, 3DVN, 3EYF, 3EYO, 3EYQ, 3FJT, 3O11, 3RY6, 3S7G, 3SGJ, 3SGK, 3TV3, 3TWC, 3TYG, 3U0W, 3U7W, 3U7Y, 3V7M, 3V8C, 3V95, 3WJJ, 3WJL, 3WKN, 3WN5, 4ACP, 4B7I, 4BM7, 4BSV, 4BSW, 4BYH, 4CDH, 4D9Q, 4D9R, 4DAG, 4DZ8, 4EOW, 4J12, 4KU1, 4LLD, 4LLM, 4LLQ, 4N0U, 4NQS, 4NQT, 4NQU, 4NWT, 4NWU, 4O4Y, 4O51, 4Q6Y, 4Q74, 4Q7D, 4W4N, 4W4O, 4X4M IGHG2: 2QSC, 4HAF, 4HAG, 4L4J IGHG4: 1ADQ, 1BBJ, 2FL5, 4B53, 4C54, 4C55, 4D2N Defects in IGHG1 are a cause of multiple myeloma, which is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. Complications of multiple myeloma are bone pain, hypercalcemia, renal failure and spinal cord compression. The aberrant antibodies that are produced lead to impaired humoral immunity and patients have a high prevalence of infection. 1099 Anti-IgE polyclonal antibody IgG Protein>Polyclonal antibody Homo sapiens (Human):9606 The polyclonal antibody was isolated from the serum of an asthma patient with high titre of IgG1 anti-IgE. 1100 SB-365579 Organic molecules or materials Unknown SB-365579 is a biotinylated derivative of SB-236057 (biotin conjugated to the spiropiperidine moiety). The compound SB-236057 is a serotonin receptor 1B (5-HT1B) inverse agonist that has been identified to be teratogenic in rats, rabbits and mice.