76 LLADTTHHRPWT HWKHPWGAWDTL KVWSLEPPGPAA YSPPSPEPPRIK QDRGILVEPPRM DFDVSFLSARMR KLWELNPPQVRT SPAPTNNYTYRL TQPLGLLPSRHL QTALITIHHSLT YGNSLPPRLGPP LWAKLWVVPERA SANLSWRESWPT 13 Phage display (common panning) PMID:16928679 Protein tonB Iron(3+)-hydroxamate-binding protein fhuD Not determined. Not determined. Ph.D.-12 phage display library (X12) 77 CPAPERPQC CHASPAHNC CVISAASQC CQSFPRQLC CNRPSSWLC CTAENSSPC CKTSPAWIC CMTARTTSC CISPAQSSC CPAVPAKAC CHLAPAARC CKALMRTSC CKPLFHNTC CHHWAPTRC CHNMPAQTC 15 Phage display (common panning) PMID:16928679 Iron(3+)-hydroxamate-binding protein fhuD Protein tonB Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) 78 LHTPWHLPAPEI KSLSRHDHIHHH YHSPPHTPPAPL SFVGLVELPQNL VSRHQSWHPHDL KTLTLPLSNTSK KIMRMPRLMTRN LHFPLDYPQALG WHSPWSTPPAPS LHWPLYTPPASP 10 Phage display (common panning) PMID:16928679 Iron(3+)-hydroxamate-binding protein fhuD Protein tonB Not determined. Not determined. Ph.D.-12 phage display library (X12) 79 PQNSKIPGPTFLDPH(0.100)[72.2 ± 32.8] SMEPALPDWWWKMFK(0.088)[17.7 ± 9.4, 4.2 ± 2.3] DKPTAFVSVYLKTAL(0.013)[NA] APRPGPWLWSNADSV(0.013)[NA] GVTDSSTSNLDMPHW(0.013)[NA] PKMTLQRSNIRPSMP(0.013)[NA] PQNSKIPGPTFLDPH(0.013)[NA] LYPLHTYTPLSLPLF(0.013)[NA] 8 Phage display (common panning) 4 PMID:15528216 Galectin-3, Gal-3 Thomsen--Friedenreich glycoantigen, TFAg Not determined. Not determined. f88-15mer phage display library (X15) Fluorescence titration Dissociation constant (Kd, nM) described the binding of peptides to galectin-3. The results demonstrate that carbohydrate-mediated, metastasis-associated tumor cell adhesion could be inhibited efficiently with short synthetic peptides which do not mimic naturally occurring glycoepitopes yet bind to the galectin-3 carbohydrate recognition domain with high affinity and specificity. 80 ANTPCGPYTHDCPVKR(0.800)[72.2 ± 32.8] AYTKCSRQWRTCMTTH(0.013)[5.7 ± 2.2] LTGTCLQYQSRCGNTR(0.013)[NA] NISRCTHPFMACGKQS(0.013)[NA] PRNICSRRDPTCWTTY(0.013)[NA] 5 Phage display (common panning) 4 PMID:15528216 Galectin-3, Gal-3 Thomsen--Friedenreich glycoantigen, TFAg Not determined. Not determined. f88-Cys6 phage display library (X4CX6CX4) Fluorescence titration Dissociation constant (Kd, nM) described the binding of peptides to galectin-3. The results demonstrate that carbohydrate-mediated, metastasis-associated tumor cell adhesion could be inhibited efficiently with short synthetic peptides which do not mimic naturally occurring glycoepitopes yet bind to the galectin-3 carbohydrate recognition domain with high affinity and specificity. 81 YPYSMWKNLWPS(5) PWWFNKYLFPPI(1) ANSFWVNHPTIT(1) W-x-N-x(2)-P 3 Phage display (common panning) 2 PMID:15847166 Anti-CSFV monoclonal antibody 1B5 E(rns) glycoprotein Not determined. Not determined. Ph.D.-12 phage display library (X12) 82 SVLFDKNRGQEI(17) QTCCDKNQGIFM(2) QPYDKNRGPTLN(1) SLYDKNRGQFGS(1) VLDWKTRGKDLP(1) D-K-N-[RQ]-G 5 Phage display (common panning) 2 PMID:15847166 Anti-CSFV monoclonal antibody b4-22 E(rns) glycoprotein Not determined. Not determined. Ph.D.-12 phage display library (X12) 83 QACQNNDTCPRL(14) TCRNNDTCRAPD(1) KACSNNSTCFN(1) PQPYDKNRGPTLN(1) SLYDKNRGQFGS(1) SFFDKNSAHWSP(1) HSWDKNSSIWWP(1) TWWDKNSATVAW(1) YYNKNNASYHSS(1) AMGYNKNNDSLL(1) DLPRWPGWYKNR(1) C-x-N(2)-x-T-C, YDKN 11 Phage display (common panning) 2 PMID:15847166 Anti-CSFV monoclonal antibody 24/16 E(rns) glycoprotein Not determined. Not determined. Ph.D.-12 phage display library (X12) 84 TRTNPWPAL(8) TRTQPGRFP(7) T-R-T-x-P 2 Phage display (common panning) 3 PMID:15634921 Anti-HMW-MAA monoclonal antibody 225.28S High molecular weight melanoma-mssociated antigen, HMW-MAA Not determined. Not determined. X9 phage display library The mimotope vaccine was then generated by coupling the most suitable candidate mimotope to tetanus toxoid as an immunogenic carrier. Immunization of rabbits with this vaccine induced a specific humoral immune response directed toward the epitope recognized by the mAb 225.28S on the native HMW-MAA. 85 TPFHHQHSTGFT NPLHHEHATGWT SWFDNFLYPTHD SYFDYLYPPRPA TYWEDTLYAARV QTFFDTMYPPPL 6 Phage display (common panning) 3 PMID:15908434 Anti-TRAP monoclonal antibody Signal transduction protein TRAP Not determined. Not determined. Ph.D.-12 phage display library (X12) By sequence analysis, it was found that the TA21 (SWFDNFLYPTHD) is highly homologous to the C-terminal sequence of TRAP which is conserved among S. aureus and Staphylococcus epidermidis, suggesting that peptide TA21 may be a useful broad vaccine to protect from infection caused by various staphylococcal strains. 86 CVHSPNREC(8) CNGSPNFVC(3) CYDTTNPSC(2) CLHATSPIC(2) CFPTRTNNC(1) CLAAYPHSC(1) SPN 6 Phage display (common panning) 4 PMID:15659541 Metallo-beta-lactamase L1 Not determined. Not determined. Not determined. Ph.D.-C7C phage display library (CX7C) 87 CRLTGGKGVGC(32) CRRTNWQGAGC(6) CADPNSVRAMC(4) CADPNSVRAHC(4) CQLTGTHGAGC(2) CAAHYRVGPWC(2) [RQ]-[LR]-T-[GN]-x(2)-G-[AV]-G, A-D-P-N-S-V-R-A-[MH], A(2)-H-Y-R-V-G-P-W 6 Phage display (subtractive panning) 3 PMID:15384175 SiHa cells Not determined. Not determined. Not determined. pVIII-9aa.Cys phage display library (CX9C) To eliminate clones that bind plastic, the library was preincubated on 10 cm tissue culture dishes for 1 h at room temperature (RT) in DMEM 10% v/v FCS. SiHa cells were grown on 10 cm tissue culture dishes until they reached an 80% confluent monolayer in the conditions mentioned above. These peptides may be useful for the design of drug or gene delivery vectors for the treatment of cervical cancer. 88 GPDLPAGDS(5) GPAYSKDIR(2) GPHLPNGDA(1) GPSLKHTNM(1) GPALELESR(1) 5 Phage display (common panning) 5 PMID:15845542 Peptidyl-prolyl cis-trans isomerase A, PPIase A Not determined. Not determined. Not determined. pVIII-9aa phage display library (X9) The peptide FGPDLPAGD showed inhibition of the isomerase reaction and NMR chemical shift mapping experiments highlight the CypA interaction epitope. 89 FHLQSYH(28) 1 Phage display (common panning) 3 PMID:15528296 Anti-PSA monoclonal antibody PSA-C1 PSA-α2M complexes Not determined. Not determined. Ph.D.-7 phage display library (X7) 90 DLVRVIQ(32) 1 Phage display (common panning) 3 PMID:15528296 Anti-PSA monoclonal antibody PSA-C2 PSA-α2M complexes Not determined. Not determined. Ph.D.-7 phage display library (X7) 91 TPSASIP(10) 1 Phage display (common panning) 3 PMID:15528296 Anti-PSA monoclonal antibody PSA-C4 PSA-α2M complexes Not determined. Not determined. Ph.D.-7 phage display library (X7) 92 FPWSQSHHQASL AYPLSLISRAPP TSSLPKLPFAPE LPYFSLSPDPFA 4 Phage display (common panning) 2 PMID:15126333 DNA repair protein XRCC3 DNA repair protein RAD51 homolog 3, R51H3 Not determined. Not determined. Ph.D.-12 phage display library (X12) 93 YKPSETIRM(2)[0.384, 72.5%] RRPRLLDTA(1)[0.479, 65.7%] 2 Phage display (common panning) 1 PMID:12657725 Anti-gastric cancer monoclonal antibody MG7 Gastric cancer-associated antigen Not determined. Not determined. pVIII-9aa phage display library (X9) ELISA The affinities of phage particles to mAb MG7 were measuered in ELISA inhibition sssay. The OD450 was measured. The inhibition rate was calculated as inhibition rate = 1 - Test OD450/MG7 OD450. 94 CPLSWPFPVFC(3)[0.288, 79.4%] CRFAPLSAVRC(2)[0.271, 80.6%] CHGPRMISFWC(1)[0.366, 73.8%] CNAIYARNAQC(1)[0.284, 79.7%] CTCHLRVYAQC(1)[0.386, 72.4%] CPLGSNHNLPC(1)[0.312, 77.7%] CGSAVRRPSRC(1)[0.381, 72.7%] CSLDLHPLRSC(1)[0.316, 77.4%] CRMCKGCYTSC(1)[0.288, 79.4%] CSWAPVYARNC(1)[0.268, 80.8%] 10 Phage display (common panning) 1 PMID:12657725 Anti-gastric cancer monoclonal antibody MG7 Gastric cancer-associated antigen Not determined. Not determined. pVIII-9aa.Cys phage display library (CX9C) ELISA The affinities of phage particles to mAb MG7 were measuered in ELISA inhibition sssay. The OD450 was measured. The inhibition rate was calculated as inhibition rate = 1 - Test OD450/MG7 OD450. 95 YHWYGYTPQNVI QIQVFHRWMTGP 2 Phage display (common panning) 3 PMID:16319141 Epidermal growth factor receptor Pro-epidermal growth factor, EGF 1IVO,1NQL,3NJP, Not determined. Ph.D.-12 phage display library (X12) Competitive binding assay and Scatchard analysis revealed that GE11 peptide (YHWYGYTPQNVI) bound specifically and efficiently to EGFR with a dissociation constant of ~22 nM, but with much lower mitogenic activity than with EGF. 96 QCTGPNVATNCR(6) QCTGPNFATNCR(1) TCNGPSVYMNCL(1) 3 Phage display (common panning) PMID:15905554 Anti-HMW-MAA monoclonal antibody 763.74 High molecular weight melanoma-mssociated antigen, HMW-MAA Not determined. Not determined. LX-8 phage display library (XCX8CX) 97 TCRLPFQNVACH(2) SCLLPFQNIFCS(2) 2 Phage display (common panning) PMID:15905554 Anti-HMW-MAA monoclonal antibody GH786 High molecular weight melanoma-mssociated antigen, HMW-MAA Not determined. Not determined. LX-8 phage display library (XCX8CX) 98 NQLPQYMGPAPAYMR(6) 1 Phage display (common panning) PMID:15905554 Anti-HMW-MAA monoclonal antibody GH786 High molecular weight melanoma-mssociated antigen, HMW-MAA Not determined. Not determined. X15 phage display library 99 LLGPYELWELSH(25) HPRPYHHTLPLT(1) 2 Phage display (subtractive panning) 3 PMID:15536075 Trastuzumab Receptor tyrosine-protein kinase erbB-2 1N8Z, Not determined. Ph.D.-12 phage display library (X12) Phages were preabsorbed on beads containing immobilized human normal IgG to remove any phages that were not specifically reactive with trastuzumab. According to the paper, peptide LLGPYELWELSH has potential for being developed as a HER-2 vaccine for biotherapy of cancer with HER-2 overexpression. 100 QDQRTFT VPATLFR LVTHTPI PHLHPPR MSLHHSH HAIYPRH ALRTASS 7 Phage display (common panning) 3 PMID:15812883 Protein P Not determined. Not determined. Not determined. Ph.D.-7 phage display library (X7)