526 60 kDa chaperonin Protein>Others P0A6F5 Protein Cpn60 GroEL protein Escherichia coli (strain K12):83333 1AON, 1DK7, 1DKD, 1FY9, 1FYA, 1GR5, 1GRL, 1GRU, 1J4Z, 1JON, 1KID, 1KP8, 1KPO, 1LA1, 1MNF, 1OEL, 1PCQ, 1PF9, 1SS8, 1SVT, 1SX3, 1SX4, 1XCK, 2C7C, 2C7D, 2C7E, 2CGT, 2EU1, 2NWC, 2YEY, 3C9V, 3CAU, 4AAQ, 4AAR, 4AAS, 4AAU, 4AB2, 4AB3 527 Anti-Cyt b monoclonal antibodies 7D5 Protein>Monoclonal antibody Mus musculus (Mouse):10090 528 Collagenase 3 Protein>Enzyme P45452 Matrix metalloproteinase-13, MMP-13 EC=3.4.24.- Homo sapiens (Human):9606 1EUB, 1FLS, 1FM1, 1PEX, 1XUC, 1XUD, 1XUR, 1YOU, 1ZTQ, 2D1N, 2E2D, 2OW9, 2OZR, 2PJT, 2YIG, 3ELM, 3I7G, 3I7I, 3KEC, 3KEJ, 3KEK, 3KRY, 3LJZ, 3O2X, 3TVC, 3ZXH, 456C, 4A7B, 830C 529 Human spermatozoa Cell Homo sapiens (Human):9606 530 Envelope glycoprotein gp120 (SU) Protein>Others P04578 [33-511] Glycoprotein 120, gp120 Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B) (HIV-1):11706 1AIK, 1DF4, 1DF5, 1DLB, 1G9M, 1GC1, 1GZL, 1K33, 1K34, 1RZJ, 2CMR, 2NY7, 2PV6, 2XRA, 3DNL, 3DNN, 3DNO, 3IDX, 3IDY, 3TYG, 3VIE, 4JPJ, 4JPK The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. This peculiar 2 stage receptor-interaction strategy allows gp120 to maintain the highly conserved coreceptor-binding site in a cryptic conformation, protected from neutralizing antibodies. Surface protein gp120 (SU) may target the virus to gut-associated lymphoid tissue (GALT) by binding host ITGA4/ITGB7 (alpha-4/beta-7 integrins), a complex that mediates T-cell migration to the GALT. The surface protein gp120 is also a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses. These interactions allow capture of viral particles at mucosal surfaces by these cells and subsequent transmission to permissive cells. 531 Mosquito salivary gland Organ and tissue Anopheles gambiae (African malaria mosquito):7165 532 Mosquito midgut lumen Organ and tissue Anopheles gambiae (African malaria mosquito):7165 533 TrpE protein Protein>Others P00895 Anthranilate synthase component 1 Anthranilate synthase component I Escherichia coli (strain K12):83333 534 p85-N-SH2 domain Protein>Others O00459 [330-425] p85 alternative name(s): Phosphatidylinositol 3-kinase regulatory subunit beta PtdIns-3-kinase regulatory subunit beta PI3-kinase regulatory subunit beta PI3K regulatory subunit beta Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta PtdIns-3-kinase regulatory subunit p85-beta PI3-kinase subunit p85-beta Homo sapiens (Human):9606 2KT1, 2XS6, 3MTT, 3O5Z 535 p85-C-SH2 domain Protein>Enzyme O00459 [622-716] p85 alternative name(s): Phosphatidylinositol 3-kinase regulatory subunit beta PtdIns-3-kinase regulatory subunit beta PI3-kinase regulatory subunit beta PI3K regulatory subunit beta Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta PtdIns-3-kinase regulatory subunit p85-beta PI3-kinase subunit p85-beta Homo sapiens (Human):9606 2KT1, 2XS6, 3MTT, 3O5Z 536 PLCγ1-N-SH2 domain Protein>Enzyme P19174 [550-657] PLCγ1 alternative name(s): 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 Phosphoinositide phospholipase C-gamma-1 Phospholipase C-gamma-1 PLC-gamma-1 Phospholipase C-II, PLC-II PLC-148 EC=3.1.4.11 Homo sapiens (Human):9606 1HSQ, 2HSP, 4EY0, 4FBN 537 PLCγ1-C-SH2 domain Protein>Enzyme P19174 [668-756] PLCγ1 alternative name(s): 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 Phosphoinositide phospholipase C-gamma-1 Phospholipase C-gamma-1 PLC-gamma-1 Phospholipase C-II, PLC-II PLC-148 EC=3.1.4.11 Homo sapiens (Human):9606 1HSQ, 2HSP, 4EY0, 4FBN 538 GAP-N-SH2 domain Protein>Others P20936 [181-272] GAP alternative name(s): Ras GTPase-activating protein 1, RasGAP GTPase-activating protein Ras p21 protein activator p120GAP Homo sapiens (Human):9606 1WER, 1WQ1, 2GQI, 2GSB, 2J05, 2J06, 2M51, 4FSS 539 GAP-C-SH2 domain Protein>Others P20936 [351-441] GAP alternative name(s): Ras GTPase-activating protein 1, RasGAP GTPase-activating protein Ras p21 protein activator p120GAP Homo sapiens (Human):9606 1WER, 1WQ1, 2GQI, 2GSB, 2J05, 2J06, 2M51, 4FSS 540 GAP-N+C-SH2 (includes SH3 domain) Protein>Others P20936 [181-441] GAP alternative name(s): Ras GTPase-activating protein 1, RasGAP GTPase-activating protein Ras p21 protein activator p120GAP Homo sapiens (Human):9606 1WER, 1WQ1, 2GQI, 2GSB, 2J05, 2J06, 2M51, 4FSS 541 Integrin alpha-V-beta-6, integrin αVβ6 Protein>Receptor Integrin alpha-V: P06756, Integrin beta-6: P18564 Integrin alpha-V alternative name(s): Vitronectin receptor subunit alpha CD_antigen=CD51 Homo sapiens (Human):9606 Integrin alpha-V: 1JV2, 1L5G, 1M1X, 1U8C, 3IJE, 4G1E, 4G1M 542 Integrin alpha-V-beta-3, integrin αvβ3 Protein>Receptor Integrin alpha-V: P06756, Integrin beta-3: P05106 Integrin alpha-V alternative name(s): Vitronectin receptor subunit alpha CD_antigen=CD51 Integrin beta-3 alternative name(s): Platelet membrane glycoprotein IIIa, GPIIIa CD_antigen=CD61 Homo sapiens (Human):9606 Integrin alpha-V: 1JV2, 1L5G, 1M1X, 1U8C, 3IJE Integrin beta-3: 1JV2, 1KUP, 1KUZ, 1L5G, 1M1X, 1M8O, 1MK7, 1MK9, 1S4X, 1TYE, 1U8C, 2K9J, 2KNC, 2KV9, 2L1C, 2Q6W, 2RMZ, 2RN0, 2VC2, 2VDK, 2VDL, 2VDM, 2VDN, 2VDO, 2VDP, 2VDQ, 2VDR, 3FCS, 3FCU, 3IJE, 3NID, 3NIF, 3NIG 543 Hyaluronan, HA Miscellaneous Homo sapiens (Human):9606 Hyaluronan (HA), a high molecular weight glycosaminoglycan, is expressed abundantly in the extracellular matrix and on cell surfaces. 544 Transferrin receptor protein 1 Protein>Receptor P02786 TfR1, TfR, TR, Trfr T9 p90 CD_antigen=CD71 Homo sapiens (Human):9606 1CX8, 1DE4, 1SUV, 2NSU, 3KAS, 3S9L, 3S9M, 3S9N 545 M protein from patient 3 Protein>Others Homo sapiens (Human):9606 546 M protein from patient 6 Protein>Others Homo sapiens (Human):9606 547 Hhydroxyethyl radical-modified bovine serum albumin, BSA-HER Protein>Others P02769 Bos taurus (Bovine):9913 2L7U, 3V03, 4F5S 548 Acetaldehyde-modified bovine serum albumin, BSA-AcH Protein>Others P02769 Bos taurus (Bovine):9913 2L7U, 3V03, 4F5S 549 HIV-1 protease, HIV-1 PR Protein>Enzyme Q9YQ34 Human immunodeficiency virus:12721 550 Matrix metalloproteinase-14, MMP-14 Protein>Enzyme P50281 Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1 Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP MMP-X1 EC=3.4.24.80 Homo sapiens (Human):9606 1BQQ, 1BUV, 3C7X, 3MA2