251 1DJS A-B:1 [A-B]>B: GNYK(6-9)+Y15+S17+G19+F22+R35+R37+LSAE(46-49)+V51+VY(54,55)+K57+Y64+P79+E87+L89+NHYN(92-95)+K113+LPL(133-135)+D140 [A-B]>A: E160+EK(163,164)+LHA(166-168)+P170+D247+V249+R251+VYS(280-282)+AQPHI(284-288)+A315+VN(317,318)+D321+GNS(345-347) 252 1E0O A-B:1, C-D:2 [A-B]>A: Y15+G19+F22+R35+R37+V51+RL(88,89)+E91+HYN(93-95)+LPL(133-135) [C-D]>C: Y15+S17+GG(19,20)+F22+R35+R37+ERLEENHYN(87-95)+L133 [A-B]>B: EK(163,164)+LHAVP(166-170)+RS(251,252)+H254+IL(257,258)+A260+Y281+I350+F352 [C-D]>D: EKRLHAVP(163-170)+D247+R251+HR(254,255)+I257+QA(259,260) 253 3CU1 A-B:1, C-D:2, A-D:4, B-C:5 [A-B]>B: Y15+SNG(17-19)+R35+NHY(92-94)+L133+L135 [C-D]>D: Y15+S17+GG(19,20)+F22+R35+NHY(92-94)+K113+L133 [A-D]>D: N114 [B-C]>B: K112+N114+S116 [A-B]>A: QK(163,164)+LHA(166-168)+P170+N173+V249 [C-D]>C: EK(163,164)+LHA(166-168)+P170+N173 [A-D]>A: H213 [B-C]>C: QH(121,213) 254 3OJ2 A-C:1, B-D:2, A-D:3, B-C:4 [A-C]>A: PPG(19-21)+YK(23,24)+Y30+S32+G34+F37+R50+R52+LSAE(61-64)+V66+VY(69,70)+P94+ERL(102-104)+NHYN(107-110)+L148+L150 [B-D]>B: PPG(19-21)+YK(23,24)+Y30+S32+G34+F37+R50+R52+LSAE(61-64)+V66+VY(69,70)+P94+ERL(102-104)+NHYN(107-110)+K143+LPL(148-150) [A-D]>A: ENH(106-108) [B-C]>B: ENH(106-108) [A-C]>C: EKRLHAVP(163-170)+N173+V249+R251+P253+VYS(280-282)+AQPHI(284-288)+SGI(315-317)+E323+SNY(343-345) [B-D]>D: EKRLHAVP(163-170)+N173+D247+V249+R251+P253+VYS(280-282)+AQPHI(284-288)+SGI(315-317)+E323+SNY(343-345) [A-D]>D: HR(254,255) [B-C]>C: R255 255 3OJM A-B:1 [A-B]>A: EKF(14-16)+LPPG(18-21)+YK(23,24)+Y30+S32+G34+F37+R50+R52+L61+AE(63,64)+V66+VY(69,70)+Y79+P94+ERLE(102-105)+NHYN(107-110)+K143+L148+L150+S154 [A-B]>B: EKRLHAVP(163-170)+N173+VPS(222-224)+D247+VERSR(249-253)+Q259+KVYS(279-282)+AQPHI(284-288)+GI(316,317)+E323+NY(344,345) 256 4J23 A-B:1 [A-B]>B: NYK(22-24)+Y30+G34+R50+LSAESV(61-66)+E102+L104+NHYN(107-110)+K128+L148+L150 [A-B]>A: K161+EKRLHAVP(163-170)+N173+D247+VER(249-251)+VYS(280-282)+AQPH(284-287)+AG(315,316)+D321+GNS(345-347) 257 1EVT A-C:1, B-D:2, A-D:3, B-C:4 [A-C]>A: YK(8,9)+Y15+S17+GG(19,20)+F22+R35+L46+AESV(48-51)+V54+E87+L89+HYN(93-95)+LPL(133-135) [B-D]>B: YK(8,9)+K12+Y15+S17+G19+F22+R35+L46+AESV(48-51)+V54+E87+L89+HYN(93-95)+LPL(133-135) [A-D]>A: H93 [B-C]>B: H93 [A-C]>C: EK(162,163)+LHAVP(165-169)+D246+V248+R250+P252+V279+SDPQPH(281-286)+E324+N345 [B-D]>D: EK(162,163)+LHAVP(165-169)+D246+V248+R250+P252+V279+SDPQPHI(281-287)+A314+E324+N345 [A-D]>D: AG(259,260) [B-C]>C: AG(259,260) 258 3OJV A-C:1, B-D:2, A-D:3, B-C:4 [A-C]>A: G21+YK(23,24)+Y30+SNY(32-34)+P37+R50+R52+QLSAE(60-64)+V66+V69+Y70+E102+L104+NHYN(107-110)+LPL(148-150) [B-D]>B: G21+YK(23,24)+Y30+SNG(32-34)+F37+R50+L61+AESV(63-66)+VY(69,70)+Q102+L104+NHYN(107-110)+LPL(148,150)+V166 [A-D]>A: D43 [B-C]>B: D43 [A-C]>C: EK(162,163)+LHAVP(165-169)+D246+V248+R250+P252+VYS(279-281)+PQPH(283-286)+A314+V316+D320+E324+GN(344,345) [B-D]>D: EK(162,163)+LHAVP(165-169)+G244+D246+V248+R250+VYS(279-281)+PQPH(283-286)+A314+V316+E324+GN(344,345) [A-D]>D: Y154 [B-C]>C: Y154 259 1RY7 A-B:1 [A-B]>A: KF(15,16)+LPPGNYK(18-24)+Y30+SNG(32-34)+F37+R50+LSAESV(61-66)+V69+E102+L104+NHYN(107-110)+LPL(148-150)+D155 [A-B]>B: DK(160,161)+LLAVP(163-167)+R223+L246+R248+I254+Q256+KVYS(276-279)+QPHI(282-285)+KELE(319-322)+N343+F347 260 2VDO B-C:5 [B-C]>B: SYS(121-123)+NR(215,216)+A218+E220 B-C]>C: AG(408,409)+DV(410,411) 261 2VDP A-H:2, A-L:3 [A-L]>A: RNVGS(77-81)+R208+GI(210,211) [A-H]>A: R77+V79+Q82+L84+N149+I154+N158+SS(205,206)+I211+LWH(213-215) [A-L]>L: N32+YY(49,50)+N53+YAQL(91-94) [A-H]>H: DTY(31-33)+Y57+YDYY(101-104) 262 2VDQ A-H:2, A-L:3 [A-H]>A: R77+V79+Q82+L84+N149+I154+N158+SS(205,206)+I211+LWH(213-215) [A-L]>A: RNVGS(77-81)+RPGI(208-211) [A-H]>H: DTY(31-33)+Y57+YDYY(101-104) [A-L]>L: N32+YY(49,50)+N53+YAQL(91-94) 263 2VDR A-H:2, A-L:3 [A-H]>A: R77+V79+Q82+L84+N149+I154+N158+SS(205,206)+I211+LWH(213-215) [A-L]>A: RNVGS(77-81)+RPGI(208-211) [A-H]>H: DTY(31-33)+Y57+YDYY(101-104) [A-L]>L: N32+YY(49,50)+N53+YAQL(91-94) 264 4K3J A-B:1 [B-A]>B: TYYDD(124-128)+H148+DRF(190-192)+R218+KET(220-222)+T230+S286 [B-A]>A: RQ(533,534)+P537+D578+Y619+R647+K649+E656+CE(669,670)+Y673+VPGRGC(692-697)+R702 265 4O3T A-B:1 [A-B]>B: TYYDD(124-128)+E167+DRF(190-192)+R218+KETK(220-223)+T230+S286 [A-B]>A: Y513+K516+RQ(533,534)+P537+D578+Y619+K649+E656+CE(669,670)+Y673+VPGRGC(692-697)+R702 266 4O3U A-B:1 [A-B]>B: TYYDD(124-128)+H148+E167+DRF(190-192)+R218+KET(220-222)+LT(229,230)+S286 [A-B]>A: Y513+K516+RQ(533,534)+P537+D578+Y619+R647+K649+E656+CE(669,670)+Y673+VPGRGC(692-697)+R702 267 3U73 A-U:1 [A-U]>U: TNGD(8-11)+R25+T27+V29+E36+L38+L40+E42+RTL(53-55)+Y57+K62+LTE(66-68)+S101+VT(126,127)+KD(139,140)+L144+L150+H166+L168+DA(254,255)+S257 [A-U]>A: CVSNKYFSNI(19-28)+W30+NC(32,33)+GQ(39,40)+K46+H87 268 4K24 A-U:1 [A-U]>U: TNGD(8-11)+R25+T27+V29+E33+E36+L40+K50+RTL(53-55)+Y57+K62+LTE(66-68)+S101+VT(126,127)+EE(134,135)+KD(139,140)+L150+H166+H251+DA(254,255)+S257 [A-U]>A: SN(9,10)+CVSNKYFSNI(19-28)+W30+N32+Q40+K46+H87 269 4C2A A-B:1 [A-B]>B: SKVAS(7-11)+N16+D18+H37+TV(103,104)+Q127+K152+DT(175,176)+PF(198,199)+EN(225,226)+Y228+DVKAVTS(235-241) [A-B]>A: KW(1312,1313)+GSHAY(1324-1328)+RK(1334,1335)+E1359+KY(1362,1363)+FQ(1366,1367)+SK(1370,1371)+R1374+E1376+RN(1395,1396) 270 4C2B A-B:1, C-D:2, E-F:3, G-H:4, B-C:5, B-E:7, C-H:8, E-H:9 [A-B]>B: D18+H37+S39+V104+E128+K152+DT(175,176)+PF(198,199)+EN(225,226)+Y228+VKAVTS(236-241) [C-D]>D: E5+S7+A10+N16+H37+T103+QE(127,128)+K152+DT(175,176)+PF(198,199)+EN(225,226)+Y228+DVKAVTS(235-241) [E-F]>F: S7+V9+A10+H37+Q59+V104+QE(127,128)+K152+DT(175,176)+PF(198,199)+E225+Y228+DVKAVTS(235-241) [G-H]>H: S7+V9+S39+D63+T81+TV(103,104)+E128+K152+DT(175,176)+PF(198,199)+EN(225,226)+Y228+DVKAVTS(235-241) [B-C]>B: L117+R121+TL(138,139)+P141+A165+K189 [B-E]>B: R21+E40+L42+Y44+R64+E66+T68+Q88+Q90+R111+E135 [C-H]>H: R21+L42+Y44+R64+E66+T68+Q88+Q90+R111+R159 [E-H]>H: L117+TL(138,139)+P141+E162+A165+PK(188,189) [A-B]>A: DGSHAY(1323-1328)+R1334+E1359+K1362+FQ(1366,1367)+SK(1370,1371) [C-D]>C: K1312+DGSHAY(1323-1328)+RK(1334,1335)+I1343+E1359+K1362+FQ(1366,1367)+SK(1370,1371)+P1465 [E-F]>E: K1312+DGSHAY(1323-1328)+K1332+RK(1334,1335)+E1359+K1362+FQ(1366,1367)+SK(1370,1371)+E1376+Y1400 [G-H]>G: K1312+GSHAY(1324-1328)+G1330+RK(1334,1335)+E1359+K1362+FQ(1366,1367)+SK(1370,1371)+R1395 [B-C]>C: E1294+A1298+V1301+ER(1305,1306)+S1338+RR(1341,1342)+SQ(1345,1346) [B-E]>E: GP(1417,1418)+LK(1422,1423)+IR(1425,1426)+E1429+AFVLS(1437-1441)+E1445+Q1449+E1452 [C-H]>C: GP(1417,1418)+LK(1422,1423)+IR(1425,1426)+E1429+AFVLS(1437-1441)+E1445+QQ(1448,1449)+E1452 [E-H]>E: E1294+V1301+E1305+R1336+S1338+R1341+S1345 271 4HFZ A-B:1, A-D:3, C-D:4 [A-B]>A: L54+L57+G58+IM(61,62)+Y67+QH(72,73)+V75+VK(93,94)+H96+IY(99,100) [A-D]>A: N79+D84 [C-D]>C: L54+G58+IM(61,62)+Y67+QH(72,73)+VK(93,94)+H96+Y100 [A-B]>B: ETFS(17-20)+LW(22,23)+LLP(25-27) [A-D]>D: K24 [C-D]>D: ETF(17-19)+LW(22,23)+LP(26,27) 272 1X9T A-B [A-B]>A: V189+YL(192,193)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [A-B]>B: FNPVYP(11-16)+DT(18,19) The site residues were obtained through computing contacts by a distance ≤ 4Å. 273 4V4U D-H, A-S, B-T, E-W, C-U, D-U, E-V, A-W, B-S, C-T [D-V]>D: V189+YL(192,193)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [A-S]>A: V189+YL(192,193)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [B-T]>B: V189+YL(192,193)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [E-W]>E: V189+YL(192,193)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [C-U]>C: V189+YL(190-192)+RQ(197,198)+E203+K387+R389+F489+LTHV(492-495)+RFPE(498-501) [D-U]>D: D220+VT(222,223)+MP(227,228)+L287+V289+YQ(292,293)+K376+V378 [E-V]>E: D220+VT(222,223)+MP(227,228)+L287+V289+YQ(292,293)+K376+V378 [A-W]>A: D220+VT(222,223)+MP(227,228)+L287+V289+YQ(292,293)+K376+V378 [B-S]>B: D220+VT(222,223)+MP(227,228)+L287+V289+YQ(292,293)+K376+V378 [C-T]>C: D220+VT(222,223)+MP(227,228)+L287+V289+YQ(292,293)+K376+V378 [D-V]>V: FNPVYP(11-16)+DT(18,19) [A-S]>S: FNPVYP(11-16)+DT(18,19) [B-T]>T: FNPVYP(11-16)+DT(18,19) [E-W]>W: FNPVYP(11-16)+DT(18,19) [C-U]>U: FNPVYP(11-16)+DT(18,19) [D-U]>U: TFNP(10-13)+Y15+YD(17,18) [E-V]>V: TFNP(10-13)+Y15+YD(17,18) [A-W]>W: TFNP(10-13)+Y15+YD(17,18) [B-S]>S: TFNP(10-13)+Y15+YD(17,18) [C-T]>T: TFNP(10-13)+Y15+YD(17,18) The site residues were obtained through computing contacts by a distance ≤ 4Å. 274 1A4W I-H [I-H]>H: M32+F34+K36+QEL(38-40)+L65+R67+RTRY(73-76)+EKI(80-82)+M84 [I-H]>I: DFEEIP(355-360)+EY(362,363) The site residues were obtained through computing contacts by a distance ≤ 4Å. 275 1DOJ A-B:1 [A-B]>A: F34+K36+Q38+L40+L65+R67+RTRY(73-76)+EKI(80-82)+M84 [A-B]>B: DFEEIP(355-360)+EKLQ(362-365)