Search Result
| Basic Information ? help | |
|---|---|
| Descriptor | z-scale |
| Style | Physiochemical |
| Brief introduction | 1:hydrophilicity ;2:bulk;3: electronic properties |
| Number of factors | 29 |
| Method | PCA |
| Number of variables | 3 |
| Descriptor table | View |
| Application | 22 oxytocin analogues;13 Pseudopeptides;7 Pepstatin Analogues;15 Bradykinin Potentiating Pentapeptides |
| QSAR Result | view |
| References title | Peptide Quantitative Structure-Activity Relationships, a Multivariate Approach |
| DOI | 10.1021/jm00390a003 |
| Reference | Hellberg S, Sjoestroem M, Skagerberg B, et al. Peptide quantitative structure-activity relationships, a multivariate approach[J]. Journal of medicinal chemistry, 1987, 30(7): 1126-1135. |
Explanation
- Descriptor: name of amino acid descriptor.
- Style: property types of amino acid peptides, such as Physiochemical, 3D-structural and so on.
- Brief introduction: property of amino acid peptides, such as significant hydrogen bond, electronic, hydrophobic, and so on.
- Number of factors: number of property.
- Method: modelling methods used in QSAR.
- Number of variables: number of parameters derived by principal component analysis Descriptor table shows property scores of amino acids in detail.
- Application: peptide datasets characterized by this amino acid descripto.r
- QSAR Result: show QSAR model statistics in detail.